Document Detail


Differential expression of two msh-related homeobox genes Chox-7 and Chox-8 during chick limb development.
MedLine Citation:
PMID:  1346246     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have isolated two closely related cDNAs, Chox-7 and Chox-8, encoding homeodomain-containing proteins homologous to Drosophila msh. The Chox-7 and Chox-8 genes are chicken cognates of mouse Hox-7.1 and Hox-8.1, respectively. In situ hybridization using 3' regions of the cDNAs as probes revealed that the Chox-7 gene is highly expressed in the mesenchyme subjacent to the apical ectodermal ridge whereas Chox-8 expression is localized in the anterodistal mesenchymal region at early stages of limb formation, suggesting different roles during limb development. At later stages, both genes are expressed in the anterior and posterior mesenchymes and in the interdigital mesenchyme where programmed cell death occurs.
Authors:
T Nohno; S Noji; E Koyama; K Nishikawa; F Myokai; T Saito; S Taniguchi
Related Documents :
10651906 - Mouse ror2 receptor tyrosine kinase is required for the heart development and limb form...
11744376 - Microarray analysis of novel cell lines representing two stages of metanephric mesenchy...
10415346 - The forkhead gene fh1 is involved in evolutionary modification of the ascidian tadpole ...
9706696 - Uncoupling segmentation and somitogenesis in the chick presomitic mesoderm.
1907636 - Regulation of the oxidative stress response by the hpr gene in bacillus subtilis.
20423916 - Development of feline microsatellites and snps for evaluating primary cataract candidat...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biochemical and biophysical research communications     Volume:  182     ISSN:  0006-291X     ISO Abbreviation:  Biochem. Biophys. Res. Commun.     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-02-18     Completed Date:  1992-02-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372516     Medline TA:  Biochem Biophys Res Commun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  121-8     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, Kawasaki Medical School, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Animals
Base Sequence
Chick Embryo
DNA / genetics,  isolation & purification
DNA Probes
Extremities / embryology
Gene Expression Regulation
Gene Library
Genes, Homeobox*
Mice
Molecular Sequence Data
Oligodeoxyribonucleotides
Polymerase Chain Reaction
Restriction Mapping
Sequence Homology, Nucleic Acid
Chemical
Reg. No./Substance:
0/DNA Probes; 0/Oligodeoxyribonucleotides; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Induction of peroxisomal beta-oxidation genes by retinoic acid in cultured rat hepatocytes.
Next Document:  High-density lipoprotein antagonizes the inhibitory effects of oxidized low-density lipoprotein and ...