Document Detail


Differential effects of semantic processing on memory encoding.
MedLine Citation:
PMID:  20162599     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Deeper semantic processing of words leads to enhanced memory encoding (depth of processing effect). The left inferior prefrontal cortex (LIPC) and the left hippocampus are known to be involved in this effect. We tested the hypothesis that different semantic encoding processes contribute qualitatively differently to memory encoding. In a memory experiment using functional magnetic resonance imaging, we compared three different encoding tasks: a nonsemantic alphabetical, an animacy decision, and a size comparison tasks. Recognition memory was tested subsequently. We hypothesized that the size comparison task would activate brain areas involved in the processing of object features and that this would be associated with successful memory encoding. Results showed that the size comparison task led to significantly better memory encoding than the two other tasks. As with the animacy decision task, it led to stronger activation of the LIPC and left hippocampus than the nonsemantic task. Both regions also had stronger activations for later remembered than for nonremembered words. The size comparison task additionally led to stronger activation in the left anterior fusiform gyrus, which was also associated with successful memory encoding. We conclude that different types of semantic processing affect memory encoding based on distinguishable brain processes.
Authors:
Klaus Fliessbach; Corinna Buerger; Peter Trautner; Christian E Elger; Bernd Weber
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Human brain mapping     Volume:  31     ISSN:  1097-0193     ISO Abbreviation:  Hum Brain Mapp     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-19     Completed Date:  2011-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9419065     Medline TA:  Hum Brain Mapp     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1653-64     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley-Liss, Inc.
Affiliation:
Department of Epileptology, University of Bonn Medical Center, Bonn, Germany. klaus.fliessbach@ukb.uni-bonn.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Mapping
Decision Making / physiology
Female
Hippocampus / physiology*
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Mental Recall / physiology*
Neuropsychological Tests
Prefrontal Cortex / physiology*
Psychomotor Performance / physiology
Reaction Time / physiology
Recognition (Psychology) / physiology*
Semantics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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