Document Detail


Differential effects of individual trans fatty acid isomers on lipoprotein assembly and metabolism.
MedLine Citation:
PMID:  10568339     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent findings indicate that certain (t-C18:1 delta 9) but not all (t-C16:1 delta 9 and t-C18:1 delta 11) trans fatty acid isomers influence intestinal lipoprotein secretion. A mechanism is suggested that appears to be sensitive to properties associated not only with geometric configuration but also with fatty acid chain length and double bond position. This mechanism could explain, in part, the conflicting results seen among studies investigating the effects of total dietary trans fatty acids on serum lipid and lipoprotein concentrations.
Authors:
N R Matthan; P J Jones
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Nutrition reviews     Volume:  57     ISSN:  0029-6643     ISO Abbreviation:  Nutr. Rev.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-12-07     Completed Date:  1999-12-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376405     Medline TA:  Nutr Rev     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  282-4     Citation Subset:  IM    
Affiliation:
School of Dietetics and Human Nutrition, Faculty of Agricultural and Environmental Sciences, McGill University, Québec, Canada.
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MeSH Terms
Descriptor/Qualifier:
Fatty Acids / pharmacology*
Humans
Lipoproteins / drug effects*,  metabolism*
Stereoisomerism
Structure-Activity Relationship
Chemical
Reg. No./Substance:
0/Fatty Acids; 0/Lipoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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