Document Detail


Differential effects of handling on exploration in male and female rats.
MedLine Citation:
PMID:  658605     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study, sex differences in the exploratory behavior of handled and nonhandled animals were measured under conditions of both high and low stimulus variation. The apparatus used was a hole-board, which provided an exploratory response independent of ambulation. Significant effects of handling were found: nonhandled animals decreased head-dipping over days whereas handled animals maintained a high rate. Sex differences were also observed: patterns of head-dipping for males and females differed over days depending on whether objects was present (high stimulus variation) or absent (low stimulus variation) under the hole-board; females also head-dipped for longer durations than males when objects were present; further, males and females showed completely opposite patterns of exploration depending on handling treatment and on level of stimulus variation. We conclude that handling differentially affects males and females, particularly as level of stimulus variability changes.
Authors:
J Weinberg; E A Krahn; S Levine
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Developmental psychobiology     Volume:  11     ISSN:  0012-1630     ISO Abbreviation:  Dev Psychobiol     Publication Date:  1978 May 
Date Detail:
Created Date:  1978-09-01     Completed Date:  1978-09-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0164074     Medline TA:  Dev Psychobiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  251-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Corticosterone / blood
Exploratory Behavior* / physiology
Female
Handling (Psychology)*
Male
Mice
Sex Factors
Chemical
Reg. No./Substance:
50-22-6/Corticosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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