Document Detail


Differential effects of glucagon on induction of rat liver glucose-6-phosphate dehydrogenase by liver injury and dietary change.
MedLine Citation:
PMID:  1278134     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Glucagon effectively prevented the increase in glucose-6-phosphate dehodrogenase activity of rat liver following the administration of a glucose-casein mixture without altering the amount of the diet consumed. However, the increase of the enzyme level in carbon tetrachloride-injured rat liver was virtually insensitive to glucagon. The results obtained gave further evidence for the difference between these two induction mechanisms of glucose-6-phosphate dehydrogenase.
Authors:
A Watanabe; A Takesue; K Taketa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Enzyme     Volume:  21     ISSN:  0013-9432     ISO Abbreviation:  Enzyme     Publication Date:  1976  
Date Detail:
Created Date:  1976-09-01     Completed Date:  1976-09-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  1262265     Medline TA:  Enzyme     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  193-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Carbon Tetrachloride Poisoning / enzymology
Diet
Enzyme Induction / drug effects
Glucagon / pharmacology*
Glucokinase / metabolism
Glucosephosphate Dehydrogenase / biosynthesis*
Hexokinase / metabolism
Isoenzymes / metabolism
Liver / drug effects,  enzymology*
Liver Glycogen / metabolism
Male
Pyruvate Kinase / metabolism
Rats
Chemical
Reg. No./Substance:
0/Isoenzymes; 0/Liver Glycogen; 9007-92-5/Glucagon; EC 1.1.1.49/Glucosephosphate Dehydrogenase; EC 2.7.1.1/Hexokinase; EC 2.7.1.2/Glucokinase; EC 2.7.1.40/Pyruvate Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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