Document Detail


Differential effect of lithium treatment on fenfluramine-induced decreases in food intake and locomotor activity in rats.
MedLine Citation:
PMID:  22282367     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Administration of fenfluramine to rats decreased 1-h food intake and locomotor activity. Short-term (2-6 days) but not long-term (21-25 days) lithium treatment potentiated fenfluramine-induced suppression of food intake. However, neither short-term nor long-term lithium treatment had any significant effect on fenfluramine-induced suppression of locomotor activity. These findings demonstrate a differential effect of lithium treatment on fenfluramine-induced suppression of food intake and locomotor activity. Furthermore, these findings are consistent with results from several other animal and clinical studies demonstrating a differential effect of lithium treatment on two different serotonin-mediated functions.
Authors:
C S Aulakh; J Zohar; K M Wozniak; J L Hill; D L Murphy
Related Documents :
2229197 - Monoclonal antibody study of the decorated spongiome of contractile vacuole complexes o...
7334007 - Presence of asialo gm1 and glucosylceramide in the intestinal mucosa of mice and induct...
6804557 - Sponge glycoconjugates: immunological properties and localization by fluorescent antibo...
21959777 - Determinants of specific food consumption in the canary islands (spain).
8760947 - Recurrent outbreaks of salmonella enteritidis infections in a texas restaurant: phage t...
8266727 - Community nutrition survey in an urban settlement in papua new guinea.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of psychopharmacology (Oxford, England)     Volume:  5     ISSN:  0269-8811     ISO Abbreviation:  J. Psychopharmacol. (Oxford)     Publication Date:  1991 Jan 
Date Detail:
Created Date:  2012-01-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8907828     Medline TA:  J Psychopharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  149-54     Citation Subset:  -    
Affiliation:
Section on Clinical Neuropharmacology, Laboratory of Clanacal Science, National Institute of Mental Health.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Long-term administration of m-chlorophenylpiperazine to rats does not alter functional sensitivity o...
Next Document:  A comparison of a ?2-adrenoceptor antagonist (ICI 118,551), diazepam and placebo in the treatment of...