Document Detail


Differential diagnostic approach to MR imaging of white matter diseases.
MedLine Citation:
PMID:  17414999     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The purpose of this article is to explore the magnetic resonance (MR) imaging features and the advanced MR techniques for differential diagnosis of white matter diseases of the brain. RESULTS: Magnetic resonance imaging is exquisitely sensitive for detecting brain abnormalities. Particularly in the evaluation of white matter diseases, MR far outperforms any other imaging technique. Lesions that may be quite subtle or even invisible on computed tomography are often clearly seen on the MR scan. The MR signal characteristics of white matter lesions are similar and relatively nonspecific, but other distinguishing features are often present to assist in diagnosis, such as the pattern of the abnormality, location, signal intensities, and enhancement features. Advanced MR techniques, such as diffusion-weighted imaging, MR spectroscopy, and perfusion imaging, provide additional specificity to the diagnosis of demyelinating diseases. CONCLUSIONS: Conventional MR images and advanced MR techniques are very helpful in distinguishing various types of white matter disease, for assessing disease burden, and for separating acute and chronic lesions.
Authors:
John R Hesselink
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Topics in magnetic resonance imaging : TMRI     Volume:  17     ISSN:  0899-3459     ISO Abbreviation:  Top Magn Reson Imaging     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2007-04-06     Completed Date:  2007-06-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8913523     Medline TA:  Top Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  243-63     Citation Subset:  IM    
Affiliation:
Department of Radiology, UCSD Medical Center, 200 West Arbor Dr, San Diego, CA 92103-8756, USA. jhesselink@ucsd.edu
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MeSH Terms
Descriptor/Qualifier:
Brain Diseases / diagnosis*
Demyelinating Diseases / diagnosis*
Diagnosis, Differential
Humans
Magnetic Resonance Imaging / methods*
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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