Document Detail

Differential diagnosis of psoriasis.
MedLine Citation:
PMID:  17828346     Owner:  NLM     Status:  In-Process    
The clinical diagnosis of psoriasis is relatively easy, especially when the lesions consist of erythematous, silvery white scaly, sharply demarcated, indurated plaques, distributed symmetrically on the extensor surfaces of limbs, the lower back and the scalp. These clinical features reflect the histopathological findings observed in active lesions, characterized by parakeratosis, acanthosis of the epidermal ridges, tortuous and dilated blood vessels, and perivascular leukocytic infiltrate; the Munro microabscess and the spongiform pustule of Kogoj are diagnostic. Diagnostic doubts, however, may arise in several clinical variants and atypical cases (guttate psoriasis, follicular or spinulosic psoriasis, erythrodermic psoriasis, pustular psoriasis) or when the psoriatic lesions are localized in particular sites (palms, soles, scalp, body folds, penis, nails). The value of erythemato-papulosquamous psoriasiform eruptions occurring during or after the administration of a diagnostic or therapeutic agent especially in psoriatic subjects is discussed.
P Lisi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reumatismo     Volume:  59 Suppl 1     ISSN:  0048-7449     ISO Abbreviation:  Reumatismo     Publication Date:  2007  
Date Detail:
Created Date:  2007-09-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401302     Medline TA:  Reumatismo     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  56-60     Citation Subset:  IM    
Section of Clinical, Allergological and Venereological Dermatology, Department of Medical and Surgical Specialities and Public Health, University of Perugia, Perugia, Italy.
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