Document Detail


Differential diagnosis of primary aldosteronism subtypes.
MedLine Citation:
PMID:  19442332     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary aldosteronism (PA) is the most frequent endocrine form of secondary hypertension. The recognition of this disease has dramatically increased with the widespread use of a screening test in most hypertensive patients, including those who are normokalemic. Interest in PA has grown since the demonstration that aldosterone has deleterious effects that are, at least in part, independent from its effects on blood pressure. The identification of the subtype of PA is fundamental to distinguish between subtypes that benefit from surgery and subtypes that should be treated pharmacologically with mineralocorticoid receptor antagonists. This article reviews the strategies to correctly identify PA subtypes, underlining the central role of adrenal vein sampling.
Authors:
Paolo Mulatero; Chiara Bertello; Andrea Verhovez; Denis Rossato; Giuseppe Giraudo; Giulio Mengozzi; Giorgio Limerutti; Eleonora Avenatti; Davide Tizzani; Franco Veglio
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current hypertension reports     Volume:  11     ISSN:  1534-3111     ISO Abbreviation:  Curr. Hypertens. Rep.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-15     Completed Date:  2009-09-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888982     Medline TA:  Curr Hypertens Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  217-23     Citation Subset:  IM    
Affiliation:
Division of Internal Medicine and Hypertension, AOU San Giovanni Battista, Via Genova 3, 10126, Torino, Italy. paolo.mulatero@libero.it
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MeSH Terms
Descriptor/Qualifier:
Aldosterone / blood*
Animals
Blood Pressure
Diagnosis, Differential
Humans
Hyperaldosteronism* / blood,  classification,  diagnosis
Chemical
Reg. No./Substance:
52-39-1/Aldosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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