| Differential diagnosis by unenhanced FLAIR T2-weighted magnetic resonance images between solitary high grade gliomas and cerebral metastases appearing as contrast-enhancing cortico-subcortical lesions. | |
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MedLine Citation:
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PMID: 21069426 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The aim was to assess the value of unenhanced fluid-attenuated inversion recovery T2-weighted sequences (FLAIR-T2) in the differential diagnosis between solitary high-grade gliomas (HGG) and cerebral metastases (CM) appearing as contrast-enhancing cortico-subcortical lesions of the brain. In 69 patients with a contrast-enhancing cortico-subcortical brain lesion (43 HGG, and 26 CM), unenhanced FLAIR-T2 and gadolinium-enhanced FLAIR T1-weighted (Gd-FLAIR-T1) axial images have been reviewed for the involvement of the cortex adjacent to the contrast-enhancing lesion. In 27 (62.79%) out of 43 HGG, and 3 (11.53%) out of 26 CM, the cortex adjacent to the contrast-enhancing lesion showed high signal intensity on unenhanced FLAIR-T2 without enhancement at Gd-FLAIR-T1. Fischer's exact probability test was P = 0.0003 when applied to HGG versus CM categories, indicating a significant difference. The high signal intensity on unenhanced FLAIR-T2 without gadolinium-enhancement of the cortex adjacent to the enhancing lesion is more frequently associated with HGG than CM. |
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Authors:
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Carmine Franco Muccio; Annachiara Tarantino; Gennaro Esposito; Alfonso Cerase |
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Publication Detail:
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Type: Journal Article Date: 2010-11-11 |
Journal Detail:
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Title: Journal of neuro-oncology Volume: 103 ISSN: 1573-7373 ISO Abbreviation: J. Neurooncol. Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-06-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309335 Medline TA: J Neurooncol Country: United States |
Other Details:
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Languages: eng Pagination: 713-7 Citation Subset: IM |
Affiliation:
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Unit of Neuroradiology, Department of Neurosciences, Azienda Ospedaliera di Rilievo Nazionale "Gaetano Rummo", Via dell'Angelo, 1, 82100, Benevento, Italy, cfmuccio@yahoo.it. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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