Document Detail


Differential acquisition of a "working memory" task by the Roman strains of rats.
MedLine Citation:
PMID:  4034709     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty-eight male rats of the Roman strains-fourteen RHA (Roman High Avoidance) and fourteen RLA (Roman Low Avoidance)-were submitted to a positively reinforced task, the delayed reinforced alternation test (DRA), in a T-maze. Performances of RLA rats were significantly better than those of RHA; RLA rats also had higher VTE (vicarious trial and error) and spontaneous alternation (SA) scores. These data confirm the fact that RLA may acquire positively reinforced learning as rapidly, or even more rapidly, than RHA rats, and that the differences in active avoidance behavior between these strains depend more on differential freezing behavior than on learning and memory capacities. Since the delayed reinforced alternation is considered as a working memory test, our results suggest that the Roman strains could be used as a genetic model for the neurobiological study of this form of memory.
Authors:
C Guenaire; J Delacour
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiology & behavior     Volume:  34     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-10-07     Completed Date:  1985-10-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  705-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Avoidance Learning / physiology
Habituation, Psychophysiologic / physiology
Male
Memory / physiology*
Models, Genetic
Rats
Species Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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