| Differential Contributions of Conformation Extension and Domain Unfolding to Properties of Fibronectin Nanotextiles. | |
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MedLine Citation:
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PMID: 23043581 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Fibronectin (FN) textiles are built as nanometer-thick fabrics. When uniaxially loaded, these fabrics exhibit a distinct threshold between elastic and plastic deformation with increasing stretch. Fabric mechanics are modeled using an eight-chain network and two-state model, revealing that elastic properties of FN depend on conformational extension of the protein and that plastic deformation depends on domain unfolding. Our results suggest how the molecular architecture of a molecule can be exploited for designer mechanical properties of a bulk material. |
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Authors:
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Leila F Deravi; Tianxiang Su; Jeffrey A Paten; Jeffrey W Ruberti; Katia Bertoldi; Kevin Kit Parker |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-8 |
Journal Detail:
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Title: Nano letters Volume: - ISSN: 1530-6992 ISO Abbreviation: Nano Lett. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101088070 Medline TA: Nano Lett Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Disease Biophysics Group, Wyss Institute for Biologically Inspired Engineering , Boston, Massachusetts 02115, United States. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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