Document Detail


Differential 2-deoxyglucose uptake into chick brain structures during passive avoidance training.
MedLine Citation:
PMID:  6472625     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pattern of [14C]2-deoxyglucose(-6-phosphate) accumulation in the brains of 14 chicks, 24 h post hatch was investigated. Isotope was injected 1 min prior to birds pecking either a water-coated or a methylanthranilate-coated bead (passive avoidance training). Birds were killed following testing for pecking or avoidance of a similar but dry bead 30 min later. Autoradiograms of coronal and parasaggital brain sections were scanned densitometrically and uptake into 12 identified and relatively heavily labelled structures measured. Three of the structures, hyperstriatum ventrale (posterior), palaeostriatum augmentatum and lobus parolfactorius showed significantly enhanced labelling (by 10, 13 and 11%; p less than 0.001, less than 0.05 and less than 0.05 respectively) in the birds which had been trained on the methylanthranilate bead by comparison with those which had pecked at the water-coated bead. The results are discussed in relationship to other observed biochemical changes consequent on passive avoidance training.
Authors:
M Kossut; S P Rose
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroscience     Volume:  12     ISSN:  0306-4522     ISO Abbreviation:  Neuroscience     Publication Date:  1984 Jul 
Date Detail:
Created Date:  1984-10-12     Completed Date:  1984-10-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7605074     Medline TA:  Neuroscience     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  971-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Autoradiography
Avoidance Learning / physiology*
Brain / metabolism*
Brain Mapping
Chickens / physiology*
Deoxy Sugars / metabolism*
Deoxyglucose / metabolism*
Chemical
Reg. No./Substance:
0/Deoxy Sugars; 154-17-6/Deoxyglucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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