Document Detail


Different turnover of fucose residues in plasma membranes of rat liver and Morris hepatoma 7777.
MedLine Citation:
PMID:  7447935     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Half-lives and rate constants of degradation of protein-bound fucose have been determined in plasma membranes and total cell homogenates of rat liver and Morris hepatoma 7777. The existence of at least two dynamically different classes of fucose-containing glycoproteins could be demonstrated in both liver and hepatoma plasma membranes. The apparent half-lives were 8.4 and 24.5 h (host liver) and 11.5 and 33.9 h (Morris hepatoma). Since this biphasic loss of fucose residues was not observed for sialic acid [Harms & Reutter (1974) Cancer Res. 34, 3165--3172], the differences are possibly related to specific functions of fucosylated glycoproteins of the plasma membrane.
Authors:
P Vischer; W Reutter
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Biochemical journal     Volume:  190     ISSN:  0264-6021     ISO Abbreviation:  Biochem. J.     Publication Date:  1980 Jul 
Date Detail:
Created Date:  1981-02-26     Completed Date:  1981-02-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  51-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Membrane / metabolism
Fucose / metabolism*
Glycoproteins / metabolism
Half-Life
Kinetics
Liver / metabolism*
Liver Neoplasms, Experimental / metabolism*
Male
Membrane Proteins / metabolism
Rats
Chemical
Reg. No./Substance:
0/Glycoproteins; 0/Membrane Proteins; 3713-31-3/Fucose
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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