| Different response of patients with idiopathic and ischaemic dilated cardiomyopathy to exercise training. | |
| | |
MedLine Citation:
|
PMID: 10962124 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We looked at the benefits and complications of a home-based exercise programme in patients with ischaemic and idiopathic dilated cardiomyopathy. Twenty-four patients with left ventricular end-diastolic dimension >6.5 cm and fractional shortening <25% entered a cross-over trial of 8 weeks training versus 8 weeks rest. Echocardiography, electrocardiogram and cardiopulmonary exercise testing were performed at baseline, after training and after detraining. Training resulted in a higher peak oxygen consumption (26.5 versus 21.3 ml/kg/min, P=0.004), a higher peak heart rate (161 versus 152 bpm, P=0.02) and improved well-being. Patients with idiopathic dilated cardiomyopathy showed a significant increase in exercise time (879 versus 828 s, P=0.03) and peak oxygen consumption (31.3 versus 24.3 ml/kg/min, P=0.02) and a decrease in left ventricular end-diastolic dimension (6.4 versus 6.9 cm, P=0.01) and end-systolic dimension (5.3 versus 5.8 cm, P=0.04) in contrast to those with coronary artery disease, who developed a reduction in septal excursion and shortening rate following training. Complications of training were more common in those patients with ischaemic cardiomyopathy, greater left ventricular dimensions, poorer exercise tolerance and greater ventilation drive at baseline, and included fluid retention and exercise-induced ventricular tachycardia. We found that this group of patients with a dilated, poorly functioning left ventricle can safely derive benefit from a home-based exercise programme, particularly those of idiopathic origin, but they should be closely monitored for the development of complications. |
| | |
Authors:
|
K M Webb-Peploe; T P Chua; D Harrington; M Y Henein; D G Gibson; A J Coats |
Related Documents
:
|
18946484 - Efficacy of exercise, losartan, enalapril, atenolol and rilmenidine in subjects with bl... 486884 - A pilot study on left ventricular dimensions and wall stress before and after submaxima... 7446754 - Contractile function in canine right ventricle. 6488434 - Metabolic, hemodynamic, and respiratory responses to performing cardiopulmonary resusci... 1184524 - Glottal aperture during panting with voluntary limitation of tidal volume. 3498824 - The kinetics of heat production in response to active shortening in frog skeletal muscle. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: International journal of cardiology Volume: 74 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2000 Jul |
Date Detail:
|
Created Date: 2000-10-31 Completed Date: 2000-10-31 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: IRELAND |
Other Details:
|
Languages: eng Pagination: 215-24 Citation Subset: IM |
Affiliation:
|
Royal Brompton Hospital, Sydney Street, SW3 6NP, London, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cardiomyopathy, Dilated / diagnosis, rehabilitation* Cross-Over Studies Echocardiography Electrocardiography Exercise* Exercise Test Exercise Tolerance Female Follow-Up Studies Humans Male Middle Aged Myocardial Ischemia / diagnosis, rehabilitation* Oxygen Consumption Patient Compliance Probability Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The relationship of late potentials to assessment of heart rate variability in post-infarction patie...
Next Document: Some radical queries.