Document Detail

Different hemodynamic stress of the ascending aorta wall in patients with bicuspid and tricuspid aortic valve.
MedLine Citation:
PMID:  16684044     Owner:  NLM     Status:  MEDLINE    
It is unclear whether ascending aorta dilation in patients with bicuspid aortic valve is caused by abnormal hemodynamics or by a common developmental defect of the aortic valve and aortic wall. We performed an echocardiographic study to examine the differences in hemodynamic stress at the ascending aorta in patients with bicuspid and tricuspid aortic valve. We studied prospectively 58 consecutive patients referred for preoperative echocardiographic examination with aortic valve stenosis and either bicuspid or tricuspid valve and an ascending aortic diameter of </=4.5 cm. Echocardiographic examination was performed from the parasternal long-axis view using ALOKA SDD 5.500 (Aloka, Tokyo) with 3.5 MHz probe. With aortic wall tissue Doppler imaging we obtained wall motion velocity patterns from the anterolateral and posteromedial region of the ascending aorta. The tissue Doppler examination showed a significantly higher peak systolic wall velocity of the anterolateral region of the ascending aorta in patients with bicuspid aortic valve (12.2 +/- 4.3 cm/sec vs. 8.8 +/- 2.6 cm/sec, p = 0.047). We conclude that in patients with bicuspid aortic valve and aortic valve stenosis the anterolateral region of the ascending aorta is subject to greater hemodynamic stress than in patients with tricuspid aortic valve.
Matthias Bauer; Henryk Siniawski; Miralem Pasic; Beate Schaumann; Roland Hetzer
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  21     ISSN:  0886-0440     ISO Abbreviation:  J Card Surg     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-05-10     Completed Date:  2006-10-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  218-20     Citation Subset:  IM    
Deutsches Herzzentrum Berlin, Germany.
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MeSH Terms
Aorta, Thoracic / physiopathology*
Aortic Valve / abnormalities*,  ultrasonography
Aortic Valve Stenosis / physiopathology,  ultrasonography
Blood Flow Velocity / physiology*
Echocardiography, Doppler
Follow-Up Studies
Middle Aged
Prospective Studies
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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