Document Detail


Different effects of electroacupuncture on esophageal motility and serum hormones in cats with esophagitis.
MedLine Citation:
PMID:  18269654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We aim to investigate the effects of different electroacupuncture (EA) frequencies at ST-36 on esophageal motility, and to compare the effect of EA on serum gastrin (GAS), motilin (MTL), and vasoactive intestinal peptide (VIP). Thirty-two cats were divided into four equal groups. All animals underwent a Heller myotomy. After esophagitis developed two frequencies (2/15 Hz or 2/100 Hz) of EA were delivered into ST-36 (LEA group [low EA], HEA group [high EA]). Animals submitted to EA on a non-point region (EANP) were used as controls (LEANP group, HEANP group), respectively. Esophageal motility was continuously monitored. The lower esophageal sphincter pressure (LESP) decreased significantly after myotomy. The LESP decreased in both LEA and LEANP cats, and in LEA cats the pressure decrease was greater. The LESP increased in the HEA group, which was higher than that in the HEANP group (P < 0.05). High-frequency EA significantly increased the peak amplitude in esophageal peristalsis. There was a decrease in serum GAS and MTL in LEA cats compared with LEANP cats (both P < 0.01). GAS and MTL were higher in the HEA group than in the HEANP group (both P < 0.01). Serum VIP decreased in the HEA group (P < 0.05), while it increased in the LEA group (P < 0.05), compared with EANP groups, respectively. EA with a high frequency at ST-36 enhances LESP as well as esophageal motility, while EA with a low frequency decreases LESP. The effect of EA is acupoint-specific, and this effect appears to be mediated through GAS, MTL and VIP.
Authors:
X Shuai; P Xie; J Liu; Y Xiang; J Li; Y Lan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E     Volume:  21     ISSN:  1442-2050     ISO Abbreviation:  Dis. Esophagus     Publication Date:  2008  
Date Detail:
Created Date:  2008-02-13     Completed Date:  2008-04-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809160     Medline TA:  Dis Esophagus     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  170-5     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Peking University First Hospital, Beijing, China. xwshuai@yahoo.com.cn
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MeSH Terms
Descriptor/Qualifier:
Animals
Cats
Electroacupuncture*
Esophagitis / blood*,  physiopathology,  therapy*
Gastrins / blood*
Gastrointestinal Motility
Motilin / blood*
Vasoactive Intestinal Peptide / blood*
Chemical
Reg. No./Substance:
0/Gastrins; 37221-79-7/Vasoactive Intestinal Peptide; 52906-92-0/Motilin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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