Document Detail

Different effects of chorionic gonadotropin on Taenia crassiceps and Taenia solium cysticerci cultured in vitro.
MedLine Citation:
PMID:  18314702     Owner:  NLM     Status:  MEDLINE    
Hormones play a significant role in murine Taenia crassiceps cysticercosis, and they may also participate in the susceptibility to Taenia solium cysticercosis. In the present study, in vitro effects are reported for human chorionic gonadotropin (hCG) on the larval stages of T. crassiceps (WFU strain) and T. solium. hCG effectively promotes parasite reproduction, i.e., it increases the number of buds on T. crassiceps cysticerci and the percentage of evagination and parasite length in T. solium. This is the first report in which a direct effect of hCG is reported for a parasite. hCG or mouse luteinizing hormone could be recognized by the cysticerci as mitogenic factors and contribute to the female and pregnancy bias toward susceptibility to T. crassiceps and T. solium cysticercosis, respectively.
M A Díaz-Orea; A S de Aluja; M de L Erosa; E Gomez-Conde; V O Castellanos Sánchez; K Willms; E Sciutto; G Fragoso
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of parasitology     Volume:  93     ISSN:  0022-3395     ISO Abbreviation:  J. Parasitol.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-03-04     Completed Date:  2008-03-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803124     Medline TA:  J Parasitol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1518-20     Citation Subset:  IM    
Centro de Investigación Biomédica de Oriente, Instituto Mexicano del Seguro Social, 4.5 Km, Carretera Atlixco-Metepec, C.P. 74360, Puebla, México.
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MeSH Terms
Chorionic Gonadotropin / pharmacology*
Cysticercus / drug effects*,  physiology
Reproduction / drug effects
Taenia solium / drug effects,  physiology
Reg. No./Substance:
0/Chorionic Gonadotropin

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