| Different effect of percutaneous and surgical coronary revascularization on cardiac autonomic function and inflammation in patients with stable angina. | |
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MedLine Citation:
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PMID: 17532490 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We assessed heart rate variability (HRV) and high-sensitivity C-reactive protein (CRP) serum levels in 77 patients with chronic stable angina (CSA), 47 of whom had obstructive coronary artery disease (CAD) and 30 normal or near-normal coronary arteries (NCA). The effect of percutaneous coronary interventions (PCI) and bypass surgery (CABG) on HRV and CRP was assessed in 36 patients (18 PCI, 18 CABG) 6 months after the intervention. A significant inverse correlation was found between CRP levels and HRV variables in CAD patients (best r value=-0.31, p=0.036 for very low frequency amplitude), but not in NCA patients. At follow-up, however, no significant correlation was found between CRP and HRV in PCI and CABG treated patients. Thus, while confirming the presence of a relation between cardiac autonomic dysfunction and inflammation in CAD patients, our data show that the association is lost after revascularization procedures. |
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Authors:
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Pasquale Santangeli; Gregory Angelo Sgueglia; Alfonso Sestito; Priscilla Lamendola; Luca Mariani; Fabio Infusino; Giampaolo Niccoli; Filippo Crea; Gaetano Antonio Lanza |
Publication Detail:
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Type: Letter Date: 2007-05-29 |
Journal Detail:
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Title: International journal of cardiology Volume: 127 ISSN: 1874-1754 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-06-16 Completed Date: 2008-09-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 269-70 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angina Pectoris
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blood,
physiopathology*,
surgery* Angioplasty, Transluminal, Percutaneous Coronary* C-Reactive Protein / metabolism Coronary Angiography Coronary Artery Bypass* Coronary Disease / blood, physiopathology*, surgery* Electrocardiography, Ambulatory Female Heart Rate / physiology Humans Inflammation Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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