| Different distribution patterns of cerebral microbleeds in acute ischemic stroke patients with and without hypertension. | |
| | |
MedLine Citation:
|
PMID: 19729926 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Cerebral microbleeds (CMBs) were found in patients with and without hypertension. We aimed to investigate different distribution patterns of CMBs in patients with and without hypertension. METHODS: We examined acute ischemic stroke patients using a standardized MRI protocol that included T(1), T(2) and gradient-echo T(2)*. Clinical and imaging characteristics were collected from all patients. RESULTS: Among 998 patients, CMBs were detected in 273 patients (27.3%). Of these, 62 did not have hypertension (22.7%). The incidence of CMBs among patients without hypertension (62/335, 18.5%) was lower than among those with hypertension (211/663, 31.8%; p < 0.01). The location of CMBs in patients without hypertension was limited to the cortical-subcortical (CSC) region in 40.3% (25/62) compared to 20.4% of those with hypertension (43/211; p = 0.01). No significant difference was found between CMB locations within the intra-CSC region in both groups. The severity of white matter changes and systolic blood pressure on admission were found to be independent predictors for CMBs in patients without hypertension. CONCLUSIONS: CMBs in patients with and without hypertension have different distribution patterns and may have a different pathogenesis. Blood pressure controlling is important in both groups because systolic blood pressure is an independent predictor of CMBs in patients without hypertension. |
| | |
Authors:
|
Jian Sun; Yannie Oi Yan Soo; Wynnie Wai Man Lam; Ka Sing Wong; Jin Sheng Zeng; Yu Hua Fan |
Related Documents
:
|
8210306 - Accelerated hypertension--patterns of mortality and clinical factors affecting outcome ... 2643856 - Morphologic changes during hypertension. 18712046 - Natural variances in blood pressure category among chinese adults. 15496966 - The coming epidemic: hypertension in rural kyrgyzstan, central asia. 8746636 - Will mercury manometers soon be obsolete? 7730386 - Contact areas and pressure distributions in the subtalar joint. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-08-29 |
Journal Detail:
|
Title: European neurology Volume: 62 ISSN: 1421-9913 ISO Abbreviation: Eur. Neurol. Publication Date: 2009 |
Date Detail:
|
Created Date: 2009-10-09 Completed Date: 2009-10-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0150760 Medline TA: Eur Neurol Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 298-303 Citation Subset: IM |
Copyright Information:
|
Copyright 2009 S. Karger AG, Basel. |
Affiliation:
|
State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-Sen University, Guangzhou, PR China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Brain Mapping Cerebral Cortex / blood supply, pathology, physiopathology* Cerebral Hemorrhage / complications*, pathology, physiopathology* Cerebral Infarction / complications*, pathology, physiopathology* Cerebrovascular Circulation Female Humans Hypertension / complications*, physiopathology* Image Interpretation, Computer-Assisted Magnetic Resonance Imaging Male Microcirculation Patient Selection Regression Analysis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The value of protecting the longitudinal staple line with invaginating sutures during esophageal rec...
Next Document: Long-term prognosis of patients with large subcortical infarctions.