Document Detail


Different changes in resistance index between uterine artery and uterine radial artery during early pregnancy.
MedLine Citation:
PMID:  18037605     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Changes in blood flow impedance of the uterine artery (UA) and uterine radial artery (RA) which is in the lower-extremity of the UA were examined during early pregnancy. METHODS: Blood flow impedance was assessed by transvaginal color-pulsed-Doppler-ultrasonography in 72 women from weeks 4-16 of pregnancy and expressed as a resistance index (RI). RESULTS: RA-RI remained at the late-luteal phase level until the 5th week of pregnancy, decreased until the 7th week, and remained low until the 10th week. UA-RI remained at the late-luteal phase level until the 10th week, and then gradually decreased until the 16th week. In nine women with spontaneous abortion, five out of six women with impaired growth of the gestational sac showed high RA-RI at the 6th week of pregnancy, whereas all three women with loss of fetal heart beat at the 8th week showed normal changes in RA-RI. CONCLUSIONS: Our results show different changes in blood flow impedance between the UA and RA during early pregnancy. A significant decrease of RA-RI after the 5th week may reflect vascular remodeling in the maternal-fetal interface at placentation, whereas a significant decrease of UA-RI after the 10th week may reflect changes of the whole uterine blood flow associated with uterine growth.
Authors:
H Tamura; I Miwa; K Taniguchi; R Maekawa; H Asada; T Taketani; A Matsuoka; Y Yamagata; H Ishikawa; N Sugino
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-11-22
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  23     ISSN:  1460-2350     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-17     Completed Date:  2008-03-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  England    
Other Details:
Languages:  eng     Pagination:  285-9     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Minamikogushi 1-1-1, Ube 755-8505, Japan.
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MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous / physiopathology
Adult
Arteries / ultrasonography
Female
Fetal Death
Humans
Luteal Phase
Pregnancy*
Pregnancy Complications / physiopathology
Pregnancy Trimester, First
Pregnancy Trimester, Second
Regional Blood Flow
Ultrasonography, Doppler, Color
Ultrasonography, Doppler, Pulsed
Uterus / blood supply*
Vascular Resistance*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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