| Different activation dynamics in multiple neural systems during simulated driving. | |
| | |
MedLine Citation:
|
PMID: 12112769 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Driving is a complex behavior that recruits multiple cognitive elements. We report on an imaging study of simulated driving that reveals multiple neural systems, each of which have different activation dynamics. The neural correlates of driving behavior are identified with fMRI and their modulation with speed is investigated. We decompose the activation into interpretable pieces using a novel, generally applicable approach, based upon independent component analysis. Some regions turn on or off, others exhibit a gradual decay, and yet others turn on transiently when starting or stopping driving. Signal in the anterior cingulate cortex, an area often associated with error monitoring and inhibition, decreases exponentially with a rate proportional to driving speed, whereas decreases in frontoparietal regions, implicated in vigilance, correlate with speed. Increases in cerebellar and occipital areas, presumably related to complex visuomotor integration, are activated during driving but not associated with driving speed. |
| | |
Authors:
|
Vince D Calhoun; James J Pekar; Vince B McGinty; Tulay Adali; Todd D Watson; Godfrey D Pearlson |
Related Documents
:
|
15461679 - Dynamic cortical activity during spasms in three patients with west syndrome: a multich... 15033899 - Fmri activation during spike and wave discharges in idiopathic generalized epilepsy. 21084099 - Fals with gly72ser mutation in sod1 gene: report of a family including the first autops... 16677939 - Sensitivity of single-voxel 1h-mrs in investigating the metabolism of the activated hum... 10947259 - Functional magnetic resonance imaging aided radiation treatment planning. 10981759 - An integrated functional magnetic resonance imaging procedure for preoperative mapping ... 7612719 - Temporal coding in the guinea-pig auditory cortex as revealed by optical imaging and it... 20861379 - Suppressive lateral interactions at parafoveal representations in primary visual cortex. 12793999 - Direct interstitial infusion of nk1-targeted neurotoxin into the spinal cord: a computa... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Human brain mapping Volume: 16 ISSN: 1065-9471 ISO Abbreviation: Hum Brain Mapp Publication Date: 2002 Jul |
Date Detail:
|
Created Date: 2002-07-11 Completed Date: 2002-08-21 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 9419065 Medline TA: Hum Brain Mapp Country: United States |
Other Details:
|
Languages: eng Pagination: 158-67 Citation Subset: IM |
Copyright Information:
|
Copyright 2002 Wiley-Liss, Inc. |
Affiliation:
|
Division of Psychiatric Neuro-Imaging, Department of Psychiatry, Johns Hopkins University, Baltimore, Maryland 21205, USA. vcalhoun@jhu.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Attention / physiology Automobile Driving / psychology* Brain / anatomy & histology*, physiology* Brain Mapping Cognition / physiology Eye Movements / physiology Female Functional Laterality / physiology Humans Magnetic Resonance Imaging Male Motion Perception / physiology Motor Skills / physiology* Movement / physiology* Nerve Net / anatomy & histology*, physiology* Nonlinear Dynamics Orientation / physiology Space Perception / physiology |
| Grant Support | |
ID/Acronym/Agency:
|
1P41RR15241-01/RR/NCRR NIH HHS; M01-RR00052/RR/NCRR NIH HHS |
| Comments/Corrections | |
Erratum In:
|
Hum Brain Mapp 2002 Oct;17(2):141-2 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Spatial independent component analysis of functional MRI time-series: to what extent do results depe...
Next Document: fMRI study comparing names versus pictures of objects.