| Differences in reading performance of patients with Drusen maculopathy and subretinal fibrosis after CNV. | |
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MedLine Citation:
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PMID: 16047185 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate differences in reading performance and contrast sensitivity on patients with drusen maculopathy and subretinal fibrosis after CNV (choroidal neovascularisation). METHODS: 136 patients (60 with drusen (D), 76 with fibrosis (F)) were studied. Patients were classified according to type of maculopathy and best-corrected visual acuity into groups D1 and F1 (LogMAR 0.2-0.4), groups D2 and F2 (LogMAR>0.4-0.7), and group F3 (LogMAR>0.7-1.3). Reading acuity (in LogRAD) and speed were examined with the Radner Reading charts and compared to the reading speed measured with the long paragraphs of the Zuercher Reading Test. Contrast sensitivity was measured with Pelli-Robson charts. RESULTS: The patients' distance visual acuity was comparable between the drusen and fibrotic CNV groups (D1 versus F1, D2 versus F2). The reading acuity of the corresponding groups D1 and F1 was also comparable, but F2 patients showed a statistically lower reading acuity than D2 patients (P=0.03). All reading speed measurements of the groups F1 and F2 were significantly worse than those of the corresponding groups D1 and D2 (P-values: 0.0005-0.02). The correlation of reading speed between the Radner and Zuercher texts was very high (r=0.73-0.94). The contrast sensitivity was significantly lower in all groups compared with group D1 (P<0.001), but comparable for groups F1, F2, and F3. CONCLUSIONS: Despite comparable results in distance visual acuity, patients with subretinal fibrosis after CNV had a greater reduction in reading ability than the patients with drusen. The distance visual acuity measurements alone, therefore, underestimate the real-life conditions and impact of AMD. |
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Authors:
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Sibylla Richter-Mueksch; Michael Stur; Eva Stifter; Wolfgang Radner |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2005-07-27 |
Journal Detail:
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Title: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Volume: 244 ISSN: 0721-832X ISO Abbreviation: Graefes Arch. Clin. Exp. Ophthalmol. Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-02-23 Completed Date: 2007-05-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8205248 Medline TA: Graefes Arch Clin Exp Ophthalmol Country: Germany |
Other Details:
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Languages: eng Pagination: 154-62 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Choroidal Neovascularization / complications, physiopathology* Contrast Sensitivity / physiology* Female Fibrosis / etiology, physiopathology Humans Male Middle Aged Prospective Studies Reading* Retina / pathology* Retinal Drusen / etiology, physiopathology* Scotoma / physiopathology* Visual Acuity / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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