Document Detail

Differences in mortality on the basis of complete blood count in an unselected population at the emergency department.
MedLine Citation:
PMID:  16950673     Owner:  NLM     Status:  MEDLINE    
The objective of this descriptive study was to relate hematological parameters of patients visiting the emergency department (ED) to mortality. The study included 1698 adult patients visiting the ED for any reason who underwent blood gas analysis. The results of hemoglobin concentration, leukocyte count, and platelet count were related to mortality within 7 days after admittance to the hospital. When comparing survivors and nonsurvivors, age (mean, 54 versus 63 years, p < .0001) and leukocyte count (median, 10.8 versus 13.9 x 10 (9)/L, p < .0001) showed significant differences. Further analysis was performed by dividing the group of patients according to the reference range. This showed higher mortality in the groups of patients with leukocyte counts outside the reference range (4.0-10.0 x 10 (9)/L, p < .01) and in the group of patients with platelet counts below the reference range (150-450 x 10 (9)/L, p < .0001). High mortality is also seen in the group of women with hemoglobin concentrations outside the reference range (12.1-15.7 g/dL, p < .01), for men no difference was observed. In conclusion, our study shows clinically relevant differences in mortality in hematological parameters in an unselected population at the ED, irrespective of underlying pathology.
Karen Vroonhof; Wouter W van Solinge; Maroeska M Rovers; Albert Huisman
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Laboratory hematology : official publication of the International Society for Laboratory Hematology     Volume:  12     ISSN:  1080-2924     ISO Abbreviation:  Lab Hematol     Publication Date:  2006  
Date Detail:
Created Date:  2006-09-04     Completed Date:  2006-10-24     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  9615688     Medline TA:  Lab Hematol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  134-8     Citation Subset:  IM    
Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
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MeSH Terms
Blood Cell Count / statistics & numerical data*
Chi-Square Distribution
Emergency Service, Hospital / statistics & numerical data
Hospitals, University
Middle Aged
Netherlands / epidemiology
Platelet Count / statistics & numerical data*
Predictive Value of Tests
Prospective Studies
Statistics, Nonparametric

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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