Document Detail

Differences in left ventricular dyssynchrony between high septal pacing and apical pacing in patients with normal left ventricular systolic function.
MedLine Citation:
PMID:  20350517     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: Permanent right ventricular apical pacing can result in heart failure due to ventricular mechanical dyssynchrony. The purpose of the study was to define differences in left ventricular dyssynchrony between high septal pacing and apical pacing using tissue Doppler imaging (TDI) and two-dimensional (2D) speckle-tracking echocardiography (STE). METHODS: The subjects were 60 patients with normal left ventricular systolic function who underwent implantation of a permanent pacemaker. Patients were divided into two groups with high septal pacing (n=36) and conventional right apical pacing (n=24). Left ventricular dyssynchrony was measured using TDI and 2D-STE. The time difference (TD) between the earliest and latest activated segments obtained from each systolic velocity curve by TDI was defined as TD-TDI. The time differences obtained from systolic strain curves obtained by 2D-STE were defined as TD-RS for radial strain, TD-CS for circumferential strain, and TD-LS for longitudinal strain. RESULTS: The high septal pacing group had significantly shorter TD-TDI (20.0+/-24.3ms vs. 59.7+/-43.0ms, p<0.0001), TD-RS (13.5+/-19.9ms vs. 45.8+/-24.6ms, p<0.0001), and TD-LS (42.7+/-22.0ms vs. 66.6+/-26.8ms, p=0.001) values compared to the apical pacing group. There was no significant difference in TD-CS between the two groups. CONCLUSION: Left ventricular dyssynchrony was smaller in patients with high septal pacing. The results show that 2D-STE is useful for detection of differences in left ventricular mechanical dyssynchrony in patients with permanent pacemaker implantation, in addition to TDI.
Hisao Yoshikawa; Makoto Suzuki; Naoki Tezuka; Takenori Otsuka; Kaoru Sugi
Related Documents :
20888007 - Electrocardiographic characteristics in right ventricular vs biventricular pacing in pa...
11139907 - Intermediate-term results of biventricular pacing in heart failure: correlation between...
20946287 - Altered left ventricular contraction pattern during right ventricular pacing: assessmen...
10069347 - Postmortem analysis of encapsulation around long-term ventricular endocardial pacing le...
23001517 - Tissue doppler imaging detects impaired biventricular performance shortly after congeni...
18463377 - Sudden cardiac arrest associated with early repolarization.
Publication Detail:
Type:  Journal Article     Date:  2010-03-10
Journal Detail:
Title:  Journal of cardiology     Volume:  56     ISSN:  0914-5087     ISO Abbreviation:  J Cardiol     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-09-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  44-50     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-ku, Tokyo, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cardiac Pacing, Artificial / methods*
Middle Aged
Ventricular Dysfunction, Left / physiopathology*,  ultrasonography
Ventricular Function, Left / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  N-terminal pro-BNP is a novel biomarker for integrated cardio-renal burden and early risk stratifica...
Next Document:  Oral sildenafil: Potential role in heart transplantation. Review of the literature and personal expe...