| Differences in growth of transplantable ascites hepatoma among various lines of Donryu rat. | |
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MedLine Citation:
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PMID: 2744102 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A total of 48 Donryu rats from 8 colonies of 5 lines were inoculated intravenously with 10(7) cells of the ascites hepatoma strain AH 66. All the conventional rats of the lines D-1 and D-2 died between 9 and 15 days after inoculation with a good growth of implanted tumor cells. On the other hand, SPF rats of the lines A-1, B-1, C and E survived for 60 days showing complete rejection of the implanted tumor cells. A 50% of conventionalized ex-SPF rats of the lines A-2 and B-2, which had been once established as SPF colonies, and thereafter had been "re-conventionalized", rejected the tumor cells. The present observations indicate that the microbial conditions of the animal, e.g. whether the animal is SPF or not, might play an important role in the growth of the implanted ascites hepatoma. |
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Authors:
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X D Ding; T Ishiguro; Z Sato; H Satoh |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Jikken dobutsu. Experimental animals Volume: 38 ISSN: 0007-5124 ISO Abbreviation: Jikken Dobutsu Publication Date: 1989 Apr |
Date Detail:
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Created Date: 1989-08-15 Completed Date: 1989-08-15 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 1256412 Medline TA: Jikken Dobutsu Country: JAPAN |
Other Details:
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Languages: eng Pagination: 151-4 Citation Subset: IM |
Affiliation:
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Laboratory Animal Center, Keio University School of Medicine, Tokyo, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Laboratory Liver Neoplasms, Experimental / pathology* Neoplasm Transplantation Rats Rats, Inbred Strains* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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