Document Detail

Differences in gallbladder bile lithogenicity in patients after gastrectomy and colectomy.
MedLine Citation:
PMID:  8682139     Owner:  NLM     Status:  MEDLINE    
The differences in lithogenicity of gallbladder bile, biliary lipid composition, cholesterol saturation index (CSI), cholesterol nucleation time (NT), bilirubin, and ionized calcium were compared in patients who had previously undergone gastrectomy or colectomy. The increased CSI and the rapid NT were absent in gastrectomized patients, while colectomy significantly increased the CSI and accelerated the NT. The levels of ionized calcium and unconjugated bilirubin, possibly responsible for pigment stone formation, were significantly higher in patients after gastrectomy, but were nearly absent in patients after colectomy. The results suggest that after gastrectomy the gallbladder bile indicates a trend towards pigment stone formation, whereas there is a trend towards cholesterol gallstones after colectomy. The different alterations of the gallbladder bile lithogenicity are clinically important.
K Chijiiwa; I Makino; N Kozaki; M Tanaka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes     Volume:  28     ISSN:  0014-312X     ISO Abbreviation:  Eur Surg Res     Publication Date:  1996  
Date Detail:
Created Date:  1996-08-20     Completed Date:  1996-08-20     Revised Date:  2006-11-30    
Medline Journal Info:
Nlm Unique ID:  0174752     Medline TA:  Eur Surg Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  1-7     Citation Subset:  IM    
Department of Surgery 1, Kyushu University Faculty of Medicine, Fukuoka, Japan.
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MeSH Terms
Bile / chemistry
Bile Acids and Salts / analysis
Bilirubin / analysis
Calcium / analysis
Cholelithiasis / etiology*
Cholesterol / analysis
Colectomy / adverse effects*
Gastrectomy / adverse effects*
Middle Aged
Reg. No./Substance:
0/Bile Acids and Salts; 57-88-5/Cholesterol; 635-65-4/Bilirubin; 7440-70-2/Calcium

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