| Differences in the effects of secretin and glucagon on the blood circulation of unanesthetized rats. | |
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MedLine Citation:
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PMID: 726816 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Carbonized microspheres, 15 mu in diameter and labelled with 85Sr or 51Cr were injected into the left ventricle of unanesthetized male rats to investigate the changes induced by secretin and glucagon in the distribution of cardiac output to various organs including splanchnic organs. Secretin (0.5 U/100 g i.v.) significantly increased the cardiac output distribution to the stomach, small intestine and pancreas, while the percentage distribution of the cardiac output to the heart, lungs and kidneys was unchanged. On the other hand, glucagon (10 microgram/100 g i.v.) significantly increased the cardiac output distribution to the heart, lungs and kidneys, while the distribution to the major splanchnic organs remained unchanged with the exception of hepatic arterial perfusion which was significantly increased by glucagon. |
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Authors:
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K Kitani; Y Suzuki; R Miura |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta hepato-gastroenterologica Volume: 25 ISSN: 0300-970X ISO Abbreviation: Acta Hepatogastroenterol (Stuttg) Publication Date: 1978 Dec |
Date Detail:
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Created Date: 1979-02-23 Completed Date: 1979-02-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0340734 Medline TA: Acta Hepatogastroenterol (Stuttg) Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 470-3 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cardiac Output / drug effects Glucagon / administration & dosage* Hemodynamics / drug effects* Intestine, Small / blood supply Male Pancreas / blood supply Pulmonary Circulation / drug effects Rats Regional Blood Flow / drug effects Secretin / administration & dosage* Stomach / blood supply |
| Chemical | |
Reg. No./Substance:
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1393-25-5/Secretin; 9007-92-5/Glucagon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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