Document Detail


Differences in early postnatal morbidity risk by pattern of fetal growth in Argentina.
MedLine Citation:
PMID:  1881837     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Information on a cohort of 5539 singleton births delivered at term in two hospitals in Rosario, Argentina, was used to examine differences in early postnatal morbidity between small for gestational age (SGA) infants classified by their ponderal index (PI). SGA infants with low PI (SGA-LPI) were 4.35 (90% CI: 1.50, 12.61) times more likely to have asphyxia, 13.75 (2.48, 76.31) times more likely to have hypoglycaemia and 2.32 (1.03, 5.26) times more likely to have respiratory distress (RD) than SGA infants with adequate PI (SGA-API). The increased risks of asphyxia and hypoglycaemia observed for SGA-LPI infants diminished, but remained statistically significant after controlling for the infant's gender, birthweight, gestational age and hospital of birth. There was no difference in risk of hyperbilirubinaemia between SGA-API and SGA-LPI infants. With the exception of risk of hyperbilirubinaemia, SGA-API infants carried the same risks of morbidity as non-SGA infants. The results of the study show that SGA infants do not constitute a homogeneous group with respect to their prospects for early postnatal health and survival. Furthermore, the pattern of differences in morbidity risk between SGA-API and SGA-LPI infants observed in this study is consistent with the timing hypothesis for the aetiology of variation in PI among SGA infants.
Authors:
L E Caulfield; J D Haas; J M Belizán; K M Rasmussen; B Edmonston
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Paediatric and perinatal epidemiology     Volume:  5     ISSN:  0269-5022     ISO Abbreviation:  Paediatr Perinat Epidemiol     Publication Date:  1991 Jul 
Date Detail:
Created Date:  1991-10-03     Completed Date:  1991-10-03     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8709766     Medline TA:  Paediatr Perinat Epidemiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  263-75     Citation Subset:  IM    
Affiliation:
Department of International Health, Johns Hopkins University, Baltimore, Maryland 21205.
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MeSH Terms
Descriptor/Qualifier:
Argentina
Asphyxia Neonatorum / etiology
Body Height / physiology
Body Weight / physiology
Cohort Studies
Embryonic and Fetal Development / physiology*
Female
Humans
Hyperbilirubinemia / etiology
Hypoglycemia / etiology
Infant, Newborn
Infant, Newborn, Diseases / etiology*,  physiopathology
Infant, Small for Gestational Age / physiology*
Male
Respiratory Distress Syndrome, Newborn / etiology
Risk Factors
Grant Support
ID/Acronym/Agency:
CA-0240/CA/NCI NIH HHS; T32 5 HD07331/HD/NICHD NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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