| Differences in early postnatal morbidity risk by pattern of fetal growth in Argentina. | |
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MedLine Citation:
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PMID: 1881837 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Information on a cohort of 5539 singleton births delivered at term in two hospitals in Rosario, Argentina, was used to examine differences in early postnatal morbidity between small for gestational age (SGA) infants classified by their ponderal index (PI). SGA infants with low PI (SGA-LPI) were 4.35 (90% CI: 1.50, 12.61) times more likely to have asphyxia, 13.75 (2.48, 76.31) times more likely to have hypoglycaemia and 2.32 (1.03, 5.26) times more likely to have respiratory distress (RD) than SGA infants with adequate PI (SGA-API). The increased risks of asphyxia and hypoglycaemia observed for SGA-LPI infants diminished, but remained statistically significant after controlling for the infant's gender, birthweight, gestational age and hospital of birth. There was no difference in risk of hyperbilirubinaemia between SGA-API and SGA-LPI infants. With the exception of risk of hyperbilirubinaemia, SGA-API infants carried the same risks of morbidity as non-SGA infants. The results of the study show that SGA infants do not constitute a homogeneous group with respect to their prospects for early postnatal health and survival. Furthermore, the pattern of differences in morbidity risk between SGA-API and SGA-LPI infants observed in this study is consistent with the timing hypothesis for the aetiology of variation in PI among SGA infants. |
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Authors:
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L E Caulfield; J D Haas; J M Belizán; K M Rasmussen; B Edmonston |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Paediatric and perinatal epidemiology Volume: 5 ISSN: 0269-5022 ISO Abbreviation: Paediatr Perinat Epidemiol Publication Date: 1991 Jul |
Date Detail:
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Created Date: 1991-10-03 Completed Date: 1991-10-03 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8709766 Medline TA: Paediatr Perinat Epidemiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 263-75 Citation Subset: IM |
Affiliation:
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Department of International Health, Johns Hopkins University, Baltimore, Maryland 21205. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Argentina Asphyxia Neonatorum / etiology Body Height / physiology Body Weight / physiology Cohort Studies Embryonic and Fetal Development / physiology* Female Humans Hyperbilirubinemia / etiology Hypoglycemia / etiology Infant, Newborn Infant, Newborn, Diseases / etiology*, physiopathology Infant, Small for Gestational Age / physiology* Male Respiratory Distress Syndrome, Newborn / etiology Risk Factors |
| Grant Support | |
ID/Acronym/Agency:
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CA-0240/CA/NCI NIH HHS; T32 5 HD07331/HD/NICHD NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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