Document Detail

Differences in dietary intakes, food sources and determinants of total flavonoids between Mediterranean and non-Mediterranean countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
MedLine Citation:
PMID:  22980437     Owner:  NLM     Status:  MEDLINE    
A greater adherence to the traditional Mediterranean (MED) diet is associated with a reduced risk of developing chronic diseases. This dietary pattern is based on higher consumption of plant products that are rich in flavonoids. We compared the total flavonoid dietary intakes, their food sources and various lifestyle factors between MED and non-MED countries participating in the EPIC study. Flavonoid intakes and their food sources for 35,628 subjects, aged 35-74 years and recruited between 1992 and 2000, in twenty-six study centres were estimated using standardised 24 h dietary recall software (EPIC-Soft®). An ad hoc food composition database on flavonoids was compiled using analytical data from the United States Department of Agriculture and Phenol-Explorer databases. Moreover, it was expanded to include using recipes, estimations of missing values and flavonoid retention factors. No significant differences in total flavonoid mean intake between non-MED countries (373·7 mg/d) and MED countries (370·2 mg/d) were observed. In the non-MED region, the main contributors were proanthocyanidins (48·2%) and flavan-3-ol monomers (24·9%) and the principal food sources were tea (25·7%) and fruits (32·8%). In the MED region, proanthocyanidins (59·0%) were by far the most abundant contributor and fruits (55·1%), wines (16·7%) and tea (6·8%) were the main food sources. The present study shows similar results for total dietary flavonoid intakes, but significant differences in flavonoid class intakes, food sources and some characteristics between MED and non-MED countries. These differences should be considered in studies about the relationships between flavonoid intake and chronic diseases.
Raul Zamora-Ros; Viktoria Knaze; Leila Luján-Barroso; Isabelle Romieu; Augustin Scalbert; Nadia Slimani; Anette Hjartåker; Dagrun Engeset; Guri Skeie; Kim Overvad; Lea Bredsdorff; Anne Tjønneland; Jytte Halkjær; Timothy J Key; Kay-Tee Khaw; Angela A Mulligan; Anna Winkvist; Ingegerd Johansson; H Bas Bueno-de-Mesquita; Petra H M Peeters; Peter Wallström; Ulrika Ericson; Valeria Pala; Maria Santucci de Magistris; Silvia Polidoro; Rosario Tumino; Antonia Trichopoulou; Vardis Dilis; Michael Katsoulis; José María Huerta; Virginia Martínez; María-José Sánchez; Eva Ardanaz; Pilar Amiano; Birgit Teucher; Verena Grote; Benedetta Bendinelli; Heiner Boeing; Jana Förster; Marina Touillaud; Florence Perquier; Guy Fagherazzi; Valentina Gallo; Elio Riboli; Carlos A González
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't     Date:  2012-09-14
Journal Detail:
Title:  The British journal of nutrition     Volume:  109     ISSN:  1475-2662     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-11     Completed Date:  2013-06-04     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  1498-507     Citation Subset:  IM    
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MeSH Terms
Diet, Mediterranean
Flavonoids* / classification
Food Analysis
Mediterranean Region
Middle Aged
Grant Support
11692//Cancer Research UK; G0401527//Medical Research Council; G1000143//Medical Research Council; //Cancer Research UK; //Department of Health; //Medical Research Council; //Wellcome Trust
Reg. No./Substance:
0/Flavonoids; 0/Tea

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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