Document Detail


Differences in clinical presentation and outcome in different countries for Takayasu's arteritis.
MedLine Citation:
PMID:  9110128     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Takayasu's arteritis is a chronic vasculitis, the etiology of which is still unknown. This condition involves primarily the aorta, its main branches, and the coronary and pulmonary arteries. One epidemiologic characteristic of this morbid condition is that almost all patients come from Asian and South American countries, which has led to searches in the role of genetic factors in its pathogenesis. International surveys on HLA analysis have focused on HLA-B52 and B39 disequilibrium with this morbid condition. These comparative studies have made clear the different characteristic clinical manifestations among Asian and South American countries, which will prompt further studies in relation to genetic factors in the future.
Authors:
F Numano
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in rheumatology     Volume:  9     ISSN:  1040-8711     ISO Abbreviation:  Curr Opin Rheumatol     Publication Date:  1997 Jan 
Date Detail:
Created Date:  1997-06-18     Completed Date:  1997-06-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9000851     Medline TA:  Curr Opin Rheumatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  12-5     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Tokyo Medical and Dental University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Asia
Family Health
Female
HLA Antigens / genetics
Humans
Male
South America
Takayasu Arteritis / epidemiology,  physiopathology*,  therapy
Treatment Outcome
Chemical
Reg. No./Substance:
0/HLA Antigens

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