| Differences in clinical and pathological characteristics of colorectal cancer in Arab as compared to Jewish patients in Northern Israel. | |
| | |
MedLine Citation:
|
PMID: 20396955 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The Incidence of colorectal cancer (CRC) differs in different ethnic groups. The aim of this study is to investigate clinical and pathological features of CRC in Arab as compared to Jewish patients in Northern Israel. Clinical and pathological characteristics of 480 patients with CRC treated between 1999 and 2006 were retrospectively reviewed. Eighty-five percent of the patients were Jews and 15% were Arabs. Mean age at diagnosis was 67.1 years in Jews and 58.3 years in Arabs (P < 0.001). Stage I CRC was 17.5% versus 7.2% (P < 0.05), Stage II was 35.5% versus 27.5% (P < 0.01), Stage III was 26% versus 33.3% (P:0 < 0.01) and Stage IV 21% versus 31% (P < 0.01) in Jewish and Arab patients respectively. In 40.6% of Jewish patients, cancer was well differentiated compared to 27.1% of Arab patients (P < 0.01) and poorly differentiated in 5.5% versus 10,4% (P < 0.05). Abdominal pain, constipation and weight loss were more common in Arabs than in Jews (P < 0.05). In conclusion CRC is more advanced, more aggressive and more symptomatic in Arab than in Jewish patients. Arab patients are younger at the time of diagnosis. Screening for CRC should be started at earlier age in the Arab population than the population at large. |
| | |
Authors:
|
Yelena Glushko; Walid Basher; Micha Barchana; Jamal Zidan |
Related Documents
:
|
3740025 - The role of antegrade barium studies in the evaluation of colitis. 7136415 - The value of conventional barium enema of the colon in patients with haemorrhoids. 2194645 - Abnormalities of lectin histochemistry in familial polyposis coli and hereditary nonpol... 11677205 - Periampullary adenomas and adenocarcinomas in familial adenomatous polyposis: cumulativ... 22330085 - Increased production of nitric oxide by neutrophils from patients with chronic granulom... 17509425 - Comparison of forehead and digit oximetry in surgical/trauma patients at risk for decre... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Familial cancer Volume: 9 ISSN: 1573-7292 ISO Abbreviation: Fam. Cancer Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-16 Completed Date: 2010-12-02 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100898211 Medline TA: Fam Cancer Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 327-30 Citation Subset: IM |
Affiliation:
|
Oncology Institute, Ziv Medical Center, Zefat, 13100, Israel. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Arabs / ethnology* Colorectal Neoplasms / ethnology*, pathology* Female Humans Incidence Israel / epidemiology Jews / ethnology* Male Middle Aged Neoplasm Staging Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Physicochemical, rheological and structural characteristics of starch in maize tortillas.
Next Document: Two-photon intravital multicolor imaging combined with inducible gene expression to distinguish meta...