Document Detail


Differences in ano-neorectal physiology of ileoanal and coloanal reconstructions for restorative proctectomy.
MedLine Citation:
PMID:  19207698     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Restorative proctectomy with straight coloanal anastomosis (CAA) and restorative proctocolectomy with ilealpouch-anal anastomosis (IPAA) are options for maintaining bowel integrity after rectal resection. The aim of this study was to compare clinical function and anorectal physiology in patients treated with CAA and IPAA. METHOD: Three-dimensional vector-manometry and neorectal volumetry were performed in straight CAA [53 patients (34 male)] and IPAA [61 patients (39 male)] for ulcerative colitis. Function was assessed using a 14 day incontinence diary. RESULTS: Function was similar in both groups, but neorectal compliance and threshold volumes for sensation, urge and maximum tolerated volume (MTV) were significantly higher after IPAA than after CAA. Mean pressure, vector volume and sphincter symmetry at rest were significant determinants of continence in both groups but squeeze pressure did not correlate significantly with function in either group. Threshold volume, MTV, and compliance were significantly correlated with frequency of defecation in patients with IPAA but not with CAA. CONCLUSION: A strong consistent resting anal sphincter pressure is one determinant of continence after both IPAA and CAA. Squeeze pressures do not influence the functional result. In IPAA but not CAA, the neorectum has a reservoir function which correlates with the postoperative frequency of defaecation.
Authors:
A D Rink; W Kneist; I Radinski; A Guinot-Barona; H Lang; K H Vestweber
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-02-04
Journal Detail:
Title:  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland     Volume:  12     ISSN:  1463-1318     ISO Abbreviation:  Colorectal Dis     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-05-07     Completed Date:  2010-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883611     Medline TA:  Colorectal Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  342-50     Citation Subset:  IM    
Affiliation:
Leverkusen General Hospital, Department of General Surgery, Am Gesundheitspark, Leverkusen, Germany. andreas.rink@ukmainz.de
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Anal Canal / physiology*
Colitis, Ulcerative / surgery
Defecation / physiology*
Fecal Incontinence / etiology
Follow-Up Studies
Humans
Male
Manometry
Middle Aged
Proctocolectomy, Restorative / adverse effects,  methods*
Recovery of Function*
Rectum / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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