Document Detail

Differences in Negative T Waves Between Takotsubo Cardiomyopathy and Reperfused Anterior Acute Myocardial Infarction.
MedLine Citation:
PMID:  22133904     Owner:  NLM     Status:  Publisher    
Background: In both takotsubo cardiomyopathy (TC) and reperfused anterior acute myocardial infarction (AMI), negative T waves commonly appear on the ECG in the subacute phase. This study aimed to clarify the ECG differences between these diseases. Methods and Results: We compared the ECGs with the greatest amplitude of negative T wave from 34 patients with TC and 237 patients with a first reperfused anterior AMI who were admitted within 6h of symptom onset and who had no abnormal Q-waves on discharge ECG. Time from symptom onset to recording the ECG did not differ between TC and anterior AMI (2.4±1.5 vs. 2.1±2.0 days, P=0.48). TC was associated with a greater maximal amplitude of negative T wave (1.00±0.44 vs. 0.79±0.46mV, P=0.044), and a greater number of leads with negative T waves (9.5±1.0 vs. 6.0±2.1, P<0.001). Negative T waves were consistently observed in leads -aV(R) and V(4-6), whereas negative T waves were rare in lead V(1) in TC. Negative T waves in lead -aV(R) (ie, positive T waves in lead aV(R)) and no negative T waves in lead V(1) identified TC with 94% sensitivity and 95% specificity, representing the highest diagnostic accuracy. Conclusions: During the subacute phase, deeper negative T waves were more frequently and broadly distributed, particularly around leads facing the apical region, in TC than in reperfused anterior AMI.
Masami Kosuge; Toshiaki Ebina; Kiyoshi Hibi; Noriaki Iwahashi; Kengo Tsukahara; Mitsuaki Endo; Nobuhiko Maejima; Zenko Nagashima; Hiroyuki Suzuki; Satoshi Morita; Satoshi Umemura; Kazuo Kimura
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-2
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  -     ISSN:  1347-4820     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Division of Cardiology, Yokohama City University Medical Center.
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