| Differences in coronary artery plaques between target and non-target vessels. | |
| | |
MedLine Citation:
|
PMID: 19901413 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: We used intravascular ultrasound (IVUS) and virtual histology (VH) to assess the differences of plaque burden and composition between target coronary arteries containing the culprit lesion and non-target coronary arteries. METHODS: Sixty patients referred for acute (n = 19) or elective (n = 41) coronary angiography were included. The target vessel containing the culprit lesion was identified by angiography. A non-target coronary artery was chosen for comparison. The first 4 cm of each vessel were analyzed with IVUS and VH. RESULTS: Total plaque burden was higher in the target vessel compared to the non-target vessel (52.4% vs. 45.9%, a relative difference of 14.2%; p < 0.001). The plaque composition of the target vessel correlated strongly with the plaque composition of the non-target vessel, but the relative amount of necrotic core was significantly higher in the target vessels (21.7% vs 19.2%; p = 0.028), whereas the amount of fibrolipidic material was significantly greater in non-target vessels (10.6% vs. 12.7%; p = 0.035). CONCLUSIONS: We conclude that in patients with relevant coronary artery disease, plaque burden and the amount of necrotic core material are greater in the target vessel. There is a strong correlation of plaque composition between target and non-target coronary arteries. |
| | |
Authors:
|
Stefan Toggweiler; Yves Suter; Andreas W Schoenenberger; Mathias Kaspar; Peiman Jamshidi; Paul Erne |
Related Documents
:
|
9363743 - Multiplane transoesophageal echocardiographic detection of thoracic aortic plaque is a ... 17990073 - Characteristics of coronary plaques before angiographic progression determined by multi... 899563 - The femoral artery-predilection site for iatrogenic vascular injuries. causes and therapy. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
|
Title: The Journal of invasive cardiology Volume: 21 ISSN: 1557-2501 ISO Abbreviation: J Invasive Cardiol Publication Date: 2009 Nov |
Date Detail:
|
Created Date: 2009-11-10 Completed Date: 2010-02-05 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8917477 Medline TA: J Invasive Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 584-7 Citation Subset: IM |
Affiliation:
|
Division of Cardiology, Kantonsspital Luzern, Luzern, Switzerland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angina Pectoris / pathology, radiography, ultrasonography Calcinosis / pathology, radiography, ultrasonography Coronary Angiography* Coronary Artery Disease / pathology, radiography*, ultrasonography* Coronary Vessels / pathology, ultrasonography* Female Humans Male Middle Aged Necrosis Prospective Studies Severity of Illness Index Ultrasonography, Interventional* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Impact of multislice computed tomography to estimate difficulty in wire crossing in percutaneous cor...
Next Document: Provisional vs. Complex Stenting Strategy for Coronary Bifurcation Lesions: Meta-Analysis of Randomi...