Document Detail

Differences in Clinical Profile of Individuals With Severe and Markedly Elevated Coronary Artery Calcification Detected by Electron Beam Computed Tomography.
MedLine Citation:
PMID:  22842974     Owner:  NLM     Status:  Publisher    
Although several studies have demonstrated the association between coronary artery calcification (CAC) and coronary artery disease events, the underlying mechanism has not been fully elucidated. Furthermore, extensive CAC still remains a poorly understood phenomenon. The objective of this study is to determine the clinical characteristics and differences between 831 asymptomatic individuals with very high CAC scores (CACS ≥1000) and 497 asymptomatic individuals with CAC scores of 400 to 999. Individuals with CACS ≥1000 were more likely to have hypertension ([HTN]; P = .0004), hypercholesterolemia (P = .0001), diabetes mellitus ([DM] P = .005), and high body mass index ([BMI]; P = .03) compared with individuals with CACS = 400-999. On multivariable analysis, age (P < .0001) and BMI (P = .01) were found to be significant risk factors for the presence of very high CAC. While for males, age (P < .0001), hypercholesterolemia (P = .001), DM (P = .002), and obesity (P = .003) were independent risk factors; in females only HTN (P = .04) was independent risk factor.
G Koulaouzidis; D Charisopoulou; S Maffrett; M Tighe; P J Jenkins; T McArthur
Related Documents :
22464304 - Techniques and results: intracranial stenting.
22503184 - Bidirectional endovascular treatment for chronic total occlusive lesions of the femorop...
17693484 - Hypoxia divergently regulates production of reactive oxygen species in human pulmonary ...
22436874 - Outcomes after off-pump reoperative coronary artery bypass grafting.
23740494 - Extra- and intracerebral course of the recurrent artery of heubner.
17062264 - Epicardial beating heart "off-pump" ablation of atrial fibrillation in non-mitral valve...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-26
Journal Detail:
Title:  Angiology     Volume:  -     ISSN:  1940-1574     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Peroxidasin forms sulfilimine chemical bonds using hypohalous acids in tissue genesis.
Next Document:  Lanthanide-ion-tuned magnetic properties in a series of three-dimensional cyano-bridged Ln(III)W(V) ...