Document Detail


Differences in Clinical Profile of Individuals With Severe and Markedly Elevated Coronary Artery Calcification Detected by Electron Beam Computed Tomography.
MedLine Citation:
PMID:  22842974     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Although several studies have demonstrated the association between coronary artery calcification (CAC) and coronary artery disease events, the underlying mechanism has not been fully elucidated. Furthermore, extensive CAC still remains a poorly understood phenomenon. The objective of this study is to determine the clinical characteristics and differences between 831 asymptomatic individuals with very high CAC scores (CACS ≥1000) and 497 asymptomatic individuals with CAC scores of 400 to 999. Individuals with CACS ≥1000 were more likely to have hypertension ([HTN]; P = .0004), hypercholesterolemia (P = .0001), diabetes mellitus ([DM] P = .005), and high body mass index ([BMI]; P = .03) compared with individuals with CACS = 400-999. On multivariable analysis, age (P < .0001) and BMI (P = .01) were found to be significant risk factors for the presence of very high CAC. While for males, age (P < .0001), hypercholesterolemia (P = .001), DM (P = .002), and obesity (P = .003) were independent risk factors; in females only HTN (P = .04) was independent risk factor.
Authors:
G Koulaouzidis; D Charisopoulou; S Maffrett; M Tighe; P J Jenkins; T McArthur
Related Documents :
22464304 - Techniques and results: intracranial stenting.
22503184 - Bidirectional endovascular treatment for chronic total occlusive lesions of the femorop...
17693484 - Hypoxia divergently regulates production of reactive oxygen species in human pulmonary ...
22436874 - Outcomes after off-pump reoperative coronary artery bypass grafting.
23740494 - Extra- and intracerebral course of the recurrent artery of heubner.
17062264 - Epicardial beating heart "off-pump" ablation of atrial fibrillation in non-mitral valve...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-26
Journal Detail:
Title:  Angiology     Volume:  -     ISSN:  1940-1574     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Peroxidasin forms sulfilimine chemical bonds using hypohalous acids in tissue genesis.
Next Document:  Lanthanide-ion-tuned magnetic properties in a series of three-dimensional cyano-bridged Ln(III)W(V) ...