Document Detail


Differences emerge in visceral adipose tissue accumulation after selection for innate cardiovascular fitness.
MedLine Citation:
PMID:  20644556     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cardiorespiratory fitness (CRF) has been reported to be inversely associated with visceral adipose tissue (VAT) accumulation, independent of body weight. However, the confounding effect of physical activity on the association between CRF and VAT remains inadequately addressed. On the basis of maximal oxygen uptake (VO(2 max)), 143 sedentary, overweight women were dichotomized into high-fit (HF) and low-fit (LF) groups. Body composition and VAT were measured using dual-energy X-ray absorptiometry and computed tomography, respectively, and activity-related energy expenditure (AEE) was calculated using the doubly labeled water technique. No differences were observed between HF and LF for body mass index (HF 28.2 ± 1.3; LF 28.3 ± 1.31 kg m(-2)), total body weight (HF 77.5 ± 6.8; LF 77.9 ± 7.3 kg), total fat mass (HF 33.5 ± 5.1; LF 33.9 ± 4.4 kg) or AEE (HF 439.9 ± 375.4; LF 517.9 ± 298.7 kcal day(-1)). Significant differences in visceral adiposity (HF 68.5 ± 30.4; LF 91.2 ± 31.8 cm(2); P<0.001) and insulin sensitivity (HF 5.1 ± 1.8; LF 3.1 ± 2.4 S(I) × 10(-4) min(-1) μIU(-1) ml(-1); P<0.01) were observed between the HF and LF groups, independent of age, race and AEE. This study affirms previous findings that CRF is an important determinant of the accumulation of VAT, and this relationship is independent of physical activity.
Authors:
D W Brock; B A Irving; B Gower; G R Hunter
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-07-20
Journal Detail:
Title:  International journal of obesity (2005)     Volume:  35     ISSN:  1476-5497     ISO Abbreviation:  Int J Obes (Lond)     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-15     Completed Date:  2011-05-10     Revised Date:  2011-09-26    
Medline Journal Info:
Nlm Unique ID:  101256108     Medline TA:  Int J Obes (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  309-12     Citation Subset:  IM    
Affiliation:
Department of Exercise and Movement Science, University of Vermont, Burlington, VT 05405-0068, USA. dbrock@uvm.edu
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MeSH Terms
Descriptor/Qualifier:
Absorptiometry, Photon
Adult
Body Mass Index
Energy Metabolism / physiology*
Exercise / physiology
Female
Humans
Intra-Abdominal Fat / radiography*
Obesity / physiopathology,  radiography*
Oxygen Consumption / physiology*
Physical Fitness / physiology*
Grant Support
ID/Acronym/Agency:
KL2 RR084151/RR/NCRR NIH HHS; M01 RR-00032/RR/NCRR NIH HHS; M01 RR000032-43/RR/NCRR NIH HHS; P30 DK056336-10/DK/NIDDK NIH HHS; P30-DK 56336/DK/NIDDK NIH HHS; R01 DK 49779/DK/NIDDK NIH HHS; R01 DK049779-10/DK/NIDDK NIH HHS; R01 HL084151-05/HL/NHLBI NIH HHS; T32 HL007457-25/HL/NHLBI NIH HHS; T32-HL007457-25/HL/NHLBI NIH HHS
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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