Document Detail


Differences between intracutaneous and transcutaneous skin oxygen tension in chronic venous insufficiency.
MedLine Citation:
PMID:  7593157     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Data obtained from transcutaneously measured PO2 (tcPO2) were taken as an indication for a decreased oxygen supply to the skin in patients with chronic venous insufficiency III. Direct (invasive) measurements in LDS have not yet been performed. We therefore measured the intracutaneous PO2 (icPO2) in healthy skin and LDS (8 healthy volunteers and 18 patients with CVI III) with needle probes (250 microns tip diameter). The icPO2 values were compared with data of tcPO2 (37 degrees C and 44 degrees C electrode temperature). In healthy skin the mean icPO2 was about 50 mmHg and no steep PO2 gradients were found. In LDS (ulcer edge) mean PO2 values were lower than in healthy skin, however, no hypoxia or anoxia was observed. At the same site most tcPO2 (44 degrees C) values were between 0 and 5 mmHg. The mean icPO2 values from ulcer edges of different patients ranged from 6 mmHg to 42 mmHg (mean 22 mmHg). In LDS very different PO2 profiles were seen. There was no correlation between tcPO2 and icPO2 data. Our present results may suggest that skin damage in patients with CVI is not necessary associated with hypoxia.
Authors:
S Roszinski; W Schmeller
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  36     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-12-15     Completed Date:  1995-12-15     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  407-13     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Medical University of Lübeck, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Anoxia / physiopathology*
Blood Gas Monitoring, Transcutaneous
Chronic Disease
Data Interpretation, Statistical
Female
Humans
Male
Middle Aged
Oxygen / analysis*,  blood
Skin / blood supply,  metabolism*
Skin Diseases / diagnosis,  etiology*
Skin Physiological Phenomena
Varicose Ulcer / physiopathology,  ultrasonography
Venous Insufficiency / physiopathology*,  ultrasonography
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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