| Difference in tracer delay-induced effect among deconvolution algorithms in CT perfusion analysis: quantitative evaluation with digital phantoms. | |
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MedLine Citation:
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PMID: 19190251 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Institutional review board approval and informed consent were obtained. The purpose was to evaluate the differences in tracer delay-induced effects of various deconvolution algorithms for computed tomographic (CT) perfusion imaging by using digital phantoms created from actual source data. Three methods of singular value decomposition (SVD) were evaluated. For standard SVD (sSVD), the delays induced significant errors in cerebral blood flow and mean transit time. In contrast, for block-circulant SVD (bSVD), these values remained virtually unchanged, whereas for delay-corrected SVD (dSVD), mild changes were observed. bSVD was superior to sSVD and dSVD for avoiding the tracer delay-induced effects in CT perfusion imaging. |
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Authors:
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Kohsuke Kudo; Makoto Sasaki; Kuniaki Ogasawara; Satoshi Terae; Shigeru Ehara; Hiroki Shirato |
Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-02-03 |
Journal Detail:
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Title: Radiology Volume: 251 ISSN: 1527-1315 ISO Abbreviation: Radiology Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-03-31 Completed Date: 2009-04-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 241-9 Citation Subset: AIM; IM |
Affiliation:
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Advanced Medical Research Center, Iwate Medical University, 19-1 Uchimaru, Morioka 020-8505, Japan. kokudo@iwate-med.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Algorithms* Brain / metabolism*, radiography* Cerebral Angiography / instrumentation, methods* Contrast Media / administration & dosage*, pharmacokinetics* Humans Male Phantoms, Imaging Radiographic Image Enhancement / methods Radiographic Image Interpretation, Computer-Assisted / methods* Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed / instrumentation, methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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