| Difference of culprit plaque composition between patients with and without pre-infarction angina: an intravascular ultrasound radiofrequency analysis. | |
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MedLine Citation:
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PMID: 19736162 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: This study was performed to assess the differences in culprit plaque composition between patients with and without pre-infarction angina (PA) by using spectral analysis of intravascular ultrasound (IVUS) radiofrequency (RF) data. METHODS AND RESULTS: Of 57 patients consecutively admitted to our institution with acute myocardial infarction, pre-intervention IVUS RF data of culprit plaques were obtained and analysed in 35 patients after percutaneous aspiration thrombectomy. Among the 35 patients, 21 patients had PA. Culprit plaques of patients without PA consisted of a higher percentage of the necrotic core component than those with PA (minimum lumen area [MLA]) site, 21.2+/-8.9% versus 9.9+/-9.8%, p=0.0015; entire culprit lesion, 18.9+/-6.3% versus 12.0+/-9.6%, p=0.023). In contrast, culprit plaques of patients with PA contained a higher percentage of the fibrofatty component than those without PA (MLA site, 21.0+/-12.0% versus 11.5+/-7.6%, p=0.013; entire culprit lesion, 16.8+/-7.9% versus 12.1+/-5.5%, p=0.062). There was no significant difference in quantitative parameters between the patients with and without PA. CONCLUSIONS: Culprit plaques of patients with PA were different from those without PA. Plaque composition may play an important role in the occurrence of PA. |
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Authors:
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Yasutomi Higashikuni; Kengo Tanabe; Shuzou Tanimoto; Jiro Aoki; Hirosada Yamamoto; Gaku Nakazawa; Ruri Chihara; Yoshinobu Onuma; Shuji Otsuki; Atsuhiko Yagishita; Sen Yachi; Hiroyoshi Nakajima; Kazuhiro Hara |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology Volume: 5 ISSN: 1774-024X ISO Abbreviation: - Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-09-08 Completed Date: 2009-10-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101251040 Medline TA: EuroIntervention Country: France |
Other Details:
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Languages: eng Pagination: 363-9 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angina Pectoris / etiology, therapy, ultrasonography* Angioplasty, Transluminal, Percutaneous Coronary Coronary Artery Disease / complications, therapy, ultrasonography* Female Fibrosis Humans Image Interpretation, Computer-Assisted* Male Middle Aged Myocardial Infarction / etiology, therapy, ultrasonography* Necrosis Predictive Value of Tests Suction Thrombectomy / methods Ultrasonography, Interventional* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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