Document Detail


Difference of culprit plaque composition between patients with and without pre-infarction angina: an intravascular ultrasound radiofrequency analysis.
MedLine Citation:
PMID:  19736162     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: This study was performed to assess the differences in culprit plaque composition between patients with and without pre-infarction angina (PA) by using spectral analysis of intravascular ultrasound (IVUS) radiofrequency (RF) data. METHODS AND RESULTS: Of 57 patients consecutively admitted to our institution with acute myocardial infarction, pre-intervention IVUS RF data of culprit plaques were obtained and analysed in 35 patients after percutaneous aspiration thrombectomy. Among the 35 patients, 21 patients had PA. Culprit plaques of patients without PA consisted of a higher percentage of the necrotic core component than those with PA (minimum lumen area [MLA]) site, 21.2+/-8.9% versus 9.9+/-9.8%, p=0.0015; entire culprit lesion, 18.9+/-6.3% versus 12.0+/-9.6%, p=0.023). In contrast, culprit plaques of patients with PA contained a higher percentage of the fibrofatty component than those without PA (MLA site, 21.0+/-12.0% versus 11.5+/-7.6%, p=0.013; entire culprit lesion, 16.8+/-7.9% versus 12.1+/-5.5%, p=0.062). There was no significant difference in quantitative parameters between the patients with and without PA. CONCLUSIONS: Culprit plaques of patients with PA were different from those without PA. Plaque composition may play an important role in the occurrence of PA.
Authors:
Yasutomi Higashikuni; Kengo Tanabe; Shuzou Tanimoto; Jiro Aoki; Hirosada Yamamoto; Gaku Nakazawa; Ruri Chihara; Yoshinobu Onuma; Shuji Otsuki; Atsuhiko Yagishita; Sen Yachi; Hiroyoshi Nakajima; Kazuhiro Hara
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  5     ISSN:  1774-024X     ISO Abbreviation:  -     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-09-08     Completed Date:  2009-10-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  France    
Other Details:
Languages:  eng     Pagination:  363-9     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Angina Pectoris / etiology,  therapy,  ultrasonography*
Angioplasty, Transluminal, Percutaneous Coronary
Coronary Artery Disease / complications,  therapy,  ultrasonography*
Female
Fibrosis
Humans
Image Interpretation, Computer-Assisted*
Male
Middle Aged
Myocardial Infarction / etiology,  therapy,  ultrasonography*
Necrosis
Predictive Value of Tests
Suction
Thrombectomy / methods
Ultrasonography, Interventional*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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