| Difference between serum beta-human chorionic gonadotropin levels in pregnancies after in vitro maturation and in vitro fertilization treatments. | |
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MedLine Citation:
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PMID: 20579986 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To compare β-hCG levels measured as the first pregnancy test in women who conceived after in vitro maturation (IVM) or IVF. DESIGN: Retrospective matched cohort analysis. SETTING: University-based medical center. PATIENT(S): Women treated with IVM or IVF. INTERVENTION(S): We studied the first serum β-hCG levels in 104 pregnant women who were successfully treated with IVM and in another 104 women with IVF treatment. Blood samplings for β-hCG were drawn on day 12-15 after ET. The two groups were matched by age, order of pregnancy, and day of blood sampling. MAIN OUTCOME MEASURE(S): First β-hCG levels. RESULT(S): Serum β-hCG levels on days 12 to 13 after ET of IVM viable singleton pregnancies were significantly higher than those of IVF pregnancies (343.2±48.4 vs. 264.0±29.2 IU/L, 95% confidence interval [CI] 22-229). Similarly, β-hCG levels on days 14 to 15 after ET of IVM viable singleton pregnancies were higher than those of IVF pregnancies (350.1±126.4 vs. 284.4±30.2 IU/L). Similar trends were found in β-hCG levels on days 12 to 13 after ET of twin viable pregnancies (IVM, 682.1±97.7 vs. IVF, 434.5±41.8 IU/L; 95% CI 44-662). Grouped linear regression with covariance analysis showed a significant difference between IVM and IVF regression lines. CONCLUSION(S): The first serum β-hCG levels in pregnancies after IVM are consistently higher than those after IVF treatment. More studies are needed to elucidate these findings. |
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Authors:
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Benny Almog; Jana Al-Shalaty; Boaz Sheizaf; Fady Shehata; Weon-Young Son; Seang Lin Tan; Togas Tulandi |
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Publication Detail:
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Type: Journal Article Date: 2010-06-26 |
Journal Detail:
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Title: Fertility and sterility Volume: 95 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 85-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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McGill Reproductive Center, Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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