Document Detail


Dietary whey hydrolysate with exercise alters the plasma protein profile: A comprehensive protein analysis.
MedLine Citation:
PMID:  21145706     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: It has been shown that dietary whey protein accelerates glucose uptake by altering glycoregulatory enzyme activity in skeletal muscle. In the present study, we investigated the effect of dietary whey protein on endurance and glycogen resynthesis and attempted to identify plasma proteins that reflected the physical condition by a comprehensive proteomics approach. METHODS: Male c57BL/6 mice were divided into four groups: sedentary, sedentary with whey protein hydrolysate, exercise, and exercise with whey protein hydrolysate. The mice in the exercise groups performed treadmill running exercise five times per week for 4 wk. Protein profiling of plasma sample obtained from individuals was performed, as were measurements of endurance performance and the glycogen content of gastrocnemius muscle. RESULTS: After the training period, the endurance of mice fed the whey diet was improved compared with that of mice fed the control diet. Muscle glycogen content was significantly increased after 4 wk of exercise, and intake of whey protein led to a further increase in glycogen. Apolipoproteins A-II and C-I and β(2)-glycoprotein-1 were found to be altered by training combined with the intake of whey protein, without significant changes induced by exercise or whey protein alone. CONCLUSION: Results of the present study suggest that these three proteins may be potential biomarkers of improved endurance and glycogen resynthesis and part of the mechanism that mediates the benefits of whey protein.
Authors:
Wataru Aoi; Yoshikazu Takanami; Yukari Kawai; Masashi Morifuji; Jinichiro Koga; Minoru Kanegae; Kenichi Mihara; Taishi Yanohara; Jun Mukai; Yuji Naito; Toshikazu Yoshikawa
Related Documents :
8806896 - Postnatal maturation of peripheral chemoreceptor ventilatory response to o2 and co2 in ...
6770086 - The pattern of breathing following step changes of alveolar partial pressures of carbon...
7132646 - The effects of hypercapnia on the metabolic response to steady-state exercise.
2125596 - Effect of partial spinal cord ablation on exercise hyperpnea in ponies.
11824936 - Effect of altered physical loading on bone and muscle in the forearm.
15505496 - Effect of chronic exercise and angiotensin-converting enzyme inhibition on rodent thora...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-8
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  -     ISSN:  1873-1244     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Affiliation:
Laboratory of Health Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Time-efficient sparse analysis of histopathological whole slide images.
Next Document:  Diazepam autoinjector intramuscular delivery system versus diazepam rectal gel: A pharmacokinetic co...