Document Detail

Dietary strategies for improving folate status in institutionalized elderly persons.
MedLine Citation:
PMID:  19537306     Owner:  NLM     Status:  MEDLINE    
The aim of this work was to compare the efficacy of two strategies designed to improve folate status: increasing the intake of vegetables, and the consumption of a folic acid-fortified food. Residents (126) from three old people's homes in the Madrid region (Spain) were studied. To each centre a dietary intervention was assigned to be followed for 6 months: (1) the consumption of margarine fortified with 200 microg folic acid/10 g portion (centre M), (2) increasing the consumption of vegetables to three servings per day (centre V), (3) control (centre C). At the beginning and end of the intervention period the subjects' intakes, serum and erythrocyte concentrations of folate were measured. The use of fortified margarine (centre M) led to a significant increase in folate intake (260.9 microg/d), serum concentration (10.3 (sd 8.3) nmol/l) and erythrocyte concentration (638.4 nmol/l). At centre V the increase in total vegetable intake achieved was very poor; these foods met with very poor acceptance, although the intake of certain vegetables particularly rich in folate improved. Therefore, the intake of this vitamin increased a little (26.7 (sd 33.0) microg/d); erythrocyte folate concentration also increased somewhat (460.5 nmol/l), althought less than centre M. The daily consumption of margarine fortified with folic acid was the more effective strategy for improving the folate status of the study subjects.
Laura M Bermejo; Aránzazu Aparicio; Elena Rodríguez-Rodríguez; M López-Sobaler; Pedro Andrés; Rosa M Ortega
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Publication Detail:
Type:  Comparative Study; Controlled Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of nutrition     Volume:  101     ISSN:  1475-2662     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-18     Completed Date:  2009-07-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  1611-5     Citation Subset:  IM    
Departamento de Nutrición, Facultad de Farmacia, Universidad Complutense, 28040 Madrid, Spain.
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MeSH Terms
Aged, 80 and over
Erythrocytes / metabolism
Folic Acid / administration & dosage,  blood*
Food, Fortified*
Homes for the Aged
Nutritional Status
Reg. No./Substance:
59-30-3/Folic Acid; 8029-82-1/Margarine

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