Document Detail

Dietary sodium intake in a sample of adult male population in southern Italy: results of the Olivetti Heart Study.
MedLine Citation:
PMID:  20216559     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/OBJECTIVES: To assess dietary habitual sodium intake and the association between daily sodium intake and anthropometric indices, food habits and hypertension in the sample of adult male population participating in the Olivetti Heart Study. SUBJECTS/METHODS: The study population was composed of 940 men participating in the 2002-2004 follow-up examination of the Olivetti Heart Study. Blood pressure, anthropometric indices, biochemical parameters and sodium excretion in a 24-h urine collection were measured. The frequency of consumption of selected foods was estimated by a food frequency questionnaire (FFQ) capturing the previous year data. In a subgroup of the study population (n=138), the fractional excretion of sodium was estimated by endogenous lithium clearance. RESULTS: Dietary sodium intake estimated by 24 h urinary excretion was 203+/-70 mmol/day. Sodium excretion was significantly lower in treated hypertensive patients and higher in overweight/obese participants when compared with normotensive and normal-weight individuals, respectively. In addition, the inverse correlation detected in normal-weight individuals (r=-0.321; P<0.05) between fractional proximal tubular sodium reabsorption and dietary sodium intake was disrupted in overweight/obese individuals (r=0.058; P=NS). The independent determinants of 24 h urinary sodium excretion were body mass index (BMI), the occurrence of antihypertensive treatment, and frequency of consumption of pasta and cold cuts. CONCLUSIONS: Habitual salt intake in this sample of male adult population in southern Italy was well above the recommended amounts. A higher salt intake and an altered renal sodium handling were observed in overweight and obese participants. Sodium intake was only slightly reduced in hypertensive participants on pharmacological therapy.
A Venezia; G Barba; O Russo; C Capasso; V De Luca; E Farinaro; F P Cappuccio; F Galletti; G Rossi; P Strazzullo
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Publication Detail:
Type:  Journal Article     Date:  2010-03-10
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  64     ISSN:  1476-5640     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-05     Completed Date:  2010-10-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  518-24     Citation Subset:  IM    
Department of Clinical and Experimental Medicine, Federico II University of Naples Medical School, Naples, Italy.
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MeSH Terms
Aged, 80 and over
Body Mass Index*
Diet Surveys
Hypertension / drug therapy,  metabolism*,  urine
Kidney Tubules, Proximal / metabolism*
Lithium / blood,  urine
Middle Aged
Obesity / metabolism*,  urine
Reference Values
Regression Analysis
Sodium Chloride, Dietary / administration & dosage*,  metabolism,  urine
Reg. No./Substance:
0/Sodium Chloride, Dietary; 7439-93-2/Lithium

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