Document Detail

Dietary restriction, tyramine, and the use of monoamine oxidase inhibitors.
MedLine Citation:
PMID:  2592589     Owner:  NLM     Status:  MEDLINE    
The aim of this study is to provide clearer guidelines for rational, safe, and practical dietary restriction for use with monoamine oxidase inhibitors. Tyramine levels were assayed in over 100 of the controversial foods that have been associated with hypertensive reactions or reported to contain high levels of tyramine. Only a very limited number of foods appear to require absolute restriction. These include all aged cheeses, concentrated yeast extracts (e.g., Marmite), sauerkraut, and broad bean pods. Alcoholic beverages, including Chianti wine consumed in moderation, appear to be safe. Some aged meats contain relatively high levels of tyramine and require closer investigation.
K I Shulman; S E Walker; S MacKenzie; S Knowles
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical psychopharmacology     Volume:  9     ISSN:  0271-0749     ISO Abbreviation:  J Clin Psychopharmacol     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-01-22     Completed Date:  1990-01-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8109496     Medline TA:  J Clin Psychopharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  397-402     Citation Subset:  IM    
Department of Psychiatry University of Toronto, Ontario, Canada.
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MeSH Terms
Food Analysis*
Hypertension / chemically induced
Monoamine Oxidase Inhibitors / administration & dosage,  adverse effects*
Tyramine / administration & dosage*,  analysis
Reg. No./Substance:
0/Monoamine Oxidase Inhibitors; 51-67-2/Tyramine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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