Document Detail


Dietary proteins and IGF I levels in preterm infants: determinants of growth, body composition and neurodevelopment.
MedLine Citation:
PMID:  25335084     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
It has been demonstrated that a high protein diet in preterm born infants during the first weeks of life may enable a growth rate equal to that seen in utero and may also result in a better long term neurodevelopmental outcome. This diet may limit immediate postnatal growth retardation and may hence lower the risk of increased fat deposition after birth leading to the metabolic syndrome in later life. Insulin like growth factor I (IGF I) has proven to play an important role in early postnatal growth of preterm infants, but also seems to have a persisting influence on body composition in childhood. Furthermore increased IGF I concentrations in preterm infants have been associated with improved neurodevelopmental outcome.This review will elaborate on the role of dietary proteins and IGF I on growth, body composition and neurodevelopment of preterm infants. Possible causal pathways will be explored and areas for future research will be proposed.Pediatric Research (2014); doi:10.1038/pr.2014.172.
Authors:
Dana F J Yumani; Harrie N Lafeber; Mirjam M van Weissenbruch
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Publication Detail:
Type:  REVIEW     Date:  2014-10-21
Journal Detail:
Title:  Pediatric research     Volume:  -     ISSN:  1530-0447     ISO Abbreviation:  Pediatr. Res.     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-10-21     Completed Date:  -     Revised Date:  2014-10-22    
Medline Journal Info:
Nlm Unique ID:  0100714     Medline TA:  Pediatr Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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