Document Detail


Dietary predictors of perfluorinated chemicals: a study from the Danish National Birth Cohort.
MedLine Citation:
PMID:  19192827     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study investigated the association between dietary variables and plasma levels of perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) among 1076 pregnant women. Diet was assessed at midpregnancy by a food-frequency questionnaire. Mean first trimester plasma PFOS and PFOA levels were 35.1 and 5.6 ng/mL respectively. PFOS levels were positively associated (p < 0.05) with intake of red meat, animal fats, and snacks (e.g., popcorn, potato chips), whereas intake of vegetables and poultry was inversely associated. The adjusted mean differences between the 75th and 25th intake percentiles were 4.3 ng/mL [95% CI: 2.1, 6.5] for red meat 3.4 ng/mL [95% CI: 1.2, 5.6] for animal fats, and 2.0 ng/mL [95% CI: 0.3, 3.6] for snacks. Similar but weaker associations were observed for PFOA. Furthermore, a comparison between women reporting low (< or =25th percentile) red meat and high (> or =75th percentile) vegetable intake and women reporting low vegetable and high red meat intake resulted in differences in plasma PFOS and PFOA concentrations equal to 31% and 18% of mean levels, respectively. Studies quantifying levels of perfluorinated compounds in food have suggested that diet could be an important route of human exposure. The observed associations in our study between dietary variables and maternal exposure further support that conclusion.
Authors:
Thorhallur I Halldorsson; Chunyuan Fei; Jørn Olsen; Loren Lipworth; Joseph K McLaughlin; Sjurdur F Olsen
Related Documents :
19680937 - Core food of the french food supply: second total diet study.
23839907 - Methylphenidate decreases fat and carbohydrate intake in obese teenagers.
11022877 - Older adults need guidance to meet nutritional recommendations.
8500127 - Relative consumption of sucrose and other sugars: has it been a factor in reduced carie...
10696717 - A comparison of heavy metal levels in the kidneys of high arctic and mainland caribou p...
23530777 - Effect of different fruit components, aeration and cold storage at 5°c on the germinat...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental science & technology     Volume:  42     ISSN:  0013-936X     ISO Abbreviation:  Environ. Sci. Technol.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2009-02-05     Completed Date:  2009-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0213155     Medline TA:  Environ Sci Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  8971-7     Citation Subset:  IM    
Affiliation:
Maternal Nutrition Group, Department of Epidemiology Research, Statens Serum Institut, Arillerivej 5, building 305, 2300 Copenhagen, Denmark. lur@ssi.dk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Alkanesulfonic Acids / blood*
Cohort Studies
Denmark
Diet*
Feeding Behavior
Female
Fluorocarbons / blood*
Humans
Meat
Octanoic Acids / blood*
Parturition*
Pregnancy
Pregnancy Trimester, First / blood
Questionnaires
Vegetables
Chemical
Reg. No./Substance:
0/Alkanesulfonic Acids; 0/Fluorocarbons; 0/Octanoic Acids; 1763-23-1/perfluorooctane sulfonic acid; 335-67-1/perfluorooctanoic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Herbicidal effects of sulfamethoxazole in Lemna gibba: using p-aminobenzoic acid as a biomarker of e...
Next Document:  A Bayesian approach to analyzing ecotoxicological data.