| Dietary potassium bicarbonate and potassium citrate have a greater inhibitory effect than does potassium chloride on magnesium absorption in wethers. | |
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MedLine Citation:
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PMID: 10539782 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We addressed the question whether the type of anion in potassium salts affects magnesium absorption and the transmural potential difference by using wethers (n = 8) fed a control diet and diets supplemented with equimolar amounts of KHCO(3), KCl or K-citrate according to a Latin-square design. The control diet contained 10.9 g K/kg dry matter and the high K diets contained 41.3 g K/kg dry matter. Compared with the control diet, KHCO(3) and K-citrate significantly reduced apparent Mg absorption by 9.5 and 6.5%, respectively. Supplemental KCl tended to reduce (P = 0.070) group mean magnesium absorption by 5.5%. Consumption of supplemental KHCO(3) and K-citrate produced a significant increase in the transmural potential difference (serosal side = positive) by 17.1 and 20.7 mV, respectively, whereas the addition of KCl to the diet did not. The individual values for the four diets tended to show a negative correlation (r = -0.336, n = 32, P = 0.060) between the transmural potential difference and apparent magnesium absorption. We conclude that different potassium salts have different effects on magnesium absorption in ruminants as caused by different effects on the transmural potential difference. |
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Authors:
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J T Schonewille; A C Beynen; A T Van't Klooster; H Wouterse; L Ram |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of nutrition Volume: 129 ISSN: 0022-3166 ISO Abbreviation: J. Nutr. Publication Date: 1999 Nov |
Date Detail:
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Created Date: 1999-11-24 Completed Date: 1999-11-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404243 Medline TA: J Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2043-7 Citation Subset: IM |
Affiliation:
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Department of Nutrition, Faculty of Veterinary Medicine, Utrecht University, 3508 TD Utrecht, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bicarbonates / administration & dosage, pharmacology* Body Weight / drug effects Diet Hydrogen-Ion Concentration Intestinal Absorption / drug effects* Magnesium / blood, pharmacokinetics* Male Potassium Chloride / administration & dosage, pharmacology* Potassium Citrate / administration & dosage, pharmacology* Potassium Compounds / administration & dosage, pharmacology* Sheep |
| Chemical | |
Reg. No./Substance:
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0/Bicarbonates; 0/Potassium Compounds; 298-14-6/potassium bicarbonate; 6100-05-6/Potassium Citrate; 7439-95-4/Magnesium; 7447-40-7/Potassium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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