Document Detail

Dietary polyphenols: good, bad, or indifferent for your health?
MedLine Citation:
PMID:  17141749     Owner:  NLM     Status:  MEDLINE    
Flavonoids and other polyphenolic compounds have powerful antioxidant effects in vitro in many test systems, but can act as pro-oxidants in some others. Whether pro-oxidant, antioxidant, or any of the many other biological effects potentially exerted by flavonoids account for or contribute to the health benefits of diets rich in plant-derived foods and beverages is uncertain. Phenolic compounds may help to protect the gastrointestinal tract against damage by reactive species present in foods or generated within the stomach and intestines. The overall health benefit of flavonoids is uncertain, and consumption of large quantities of them in fortified foods or supplements should not yet be encouraged.
Barry Halliwell
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-10-13
Journal Detail:
Title:  Cardiovascular research     Volume:  73     ISSN:  0008-6363     ISO Abbreviation:  Cardiovasc. Res.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-12-25     Completed Date:  2007-04-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0077427     Medline TA:  Cardiovasc Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  341-7     Citation Subset:  IM    
Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, MD7 Level 2, 117597 Singapore, Singapore.
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MeSH Terms
Antioxidants / metabolism
Chelating Agents
Dietary Supplements
Flavonoids / metabolism*
Gastrointestinal Contents / microbiology
Gastrointestinal Tract / metabolism*,  microbiology
Intestinal Absorption
Phenols / metabolism*
Plants, Edible
Reg. No./Substance:
0/Antioxidants; 0/Chelating Agents; 0/Flavonoids; 0/Phenols; 0/Xenobiotics; 0/polyphenols

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