| Dietary inulin intake and age can affect intestinal absorption of zinc and copper in rats. | |
| | |
MedLine Citation:
|
PMID: 16365069 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Nondigestible inulin-type fructan intake can stimulate intestinal mineral absorption in both humans and animals. However, this stimulatory effect may depend on experimental conditions such as the duration of the experience, mineral levels in the diet, and the animal's physiological status. The aim of this study was to determine the effect of inulin intake on Zn and Cu absorption in rats at different ages. Male Wistar rats (n = 80) of 4 different ages (2,5, 10, and 20 mo) were randomly assigned to a control group or a group administered 3.75% inulin in their diet for 4 d followed by 7.5% inulin for 26 d. Absorption of Zn67 and Cu65 was determined on d 21 of the experiment by fecal monitoring using Zn67 and Cu65 isotopes. Zn and Cu status was also assessed. Absorption of Zn67 and Cu65 was significantly lower in 11- and 21-mo-old rats than in 3- and 6 mo-old-rats. Moreover, inulin intake significantly increased Zn67 and Cu65 absorption. In conclusion, age and dietary inulin intake can significantly affect intestinal absorption of zinc and copper in rats. Further studies are required to explore this effect over longer periods of inulin intake and to test the effects of inulin in humans. |
| | |
Authors:
|
Charles Coudray; Christine Feillet-Coudray; Elyett Gueux; Andrzej Mazur; Yves Rayssiguier |
Related Documents
:
|
15573929 - Plasma glp-2 levels and intestinal markers in the juvenile pig during intestinal adapta... 2841519 - The effects of diet on the residual small intestine following massive resection. 2187579 - Critical period programming of intestinal glucose transport via alterations in dietary ... 10188819 - Influence of fermentable fiber on small intestinal dimensions and transport of glucose ... 508699 - The effect of pectin on the structure and function of the rat small intestine. 1645209 - Starch and dietary fibre: their physiological and epidemiological interrelationships. 7786349 - Carbohydrate, fat, and protein condition similar flavor preferences in rats using an or... 7747169 - Formation and structure of dentine in the rat incisor after chronic exposure to sodium ... 2401649 - Mass selection for increased 70-day weight in a closed line of landrace pigs. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Journal of nutrition Volume: 136 ISSN: 0022-3166 ISO Abbreviation: J. Nutr. Publication Date: 2006 Jan |
Date Detail:
|
Created Date: 2005-12-20 Completed Date: 2006-02-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0404243 Medline TA: J Nutr Country: United States |
Other Details:
|
Languages: eng Pagination: 117-22 Citation Subset: IM |
Affiliation:
|
Centre de Recherche en Nutrition Humaine d'Auvergne, Unité Maladies Métaboliques et Micro-nutriments, INRA, Theix, France. coudray@clermont.inra.fr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aging
/
metabolism* Animals Copper / blood, pharmacokinetics* Diet Dose-Response Relationship, Drug Fermentation / drug effects Intestinal Absorption / drug effects Inulin / administration & dosage, pharmacology* Liver / drug effects*, metabolism Male Rats Rats, Wistar Zinc / blood, pharmacokinetics* |
| Chemical | |
Reg. No./Substance:
|
7440-50-8/Copper; 7440-66-6/Zinc; 9005-80-5/Inulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A lignan complex isolated from flaxseed does not affect plasma lipid concentrations or antioxidant c...
Next Document: Bread fortified with cholecalciferol increases the serum 25-hydroxyvitamin D concentration in women ...